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The Office of the Vice Chancellor for Research (OVCR) publishes the RESEARCH ENTERPRISE to keep the academic community and the community at large informed about research activities, opportunities and development on the IUPUI campus.

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Fred Haver


If you have a news item or recent noteworthy research-related achievement that you would like to share, please see the Research Enterprise Submission Guidelines.

Please be aware that not all news items will be deemed appropriate or timely for publication, but each item will be carefully considered.

June 17, 2015

INSIDE THIS ISSUE:

 

FEATURE STORY

Professor publishes second volume of authoritative biography

Ray Bradbury Unbound

Finalist for the Locus Award,
Nonfiction category, 2015

Fully established in the slick magazines, award-winning, and on the brink of placing Fahrenheit 451 in the American canon, Ray Bradbury entered the autumn of 1953 as a literary figure transcending fantasy and science fiction. In Ray Bradbury Unbound, Jonathan R. Eller continues the story begun in his acclaimed Becoming Ray Bradbury, following the beloved writer's evolution from a short story master to a multi-media creative force and outspoken visionary.

Drawn into screenwriting by the chance to adapt Moby Dick for film, Bradbury soon established himself in Hollywood's vast and overlapping film and television empires. The work swallowed up creative energy once devoted to literary pursuits and often left Bradbury frustrated with studio executives.

Yet his successes endowed him with the gravitas to emerge as a much sought after cultural commentator. His passionate advocacy in Life and other media outlets validated the U.S. space program's mission -- a favor repaid when NASA's astronauts gathered to meet Bradbury during his 1967 visit to Houston. Over time, his public addresses and interviews allowed him to assume the role of a dreamer of futures voicing opinions on technology, the moon landing, and humanity's ultimate destiny.

Eller draws on many years of interviews with Bradbury as well as an unprecedented access to personal papers and private collections to portray the origins and outcomes of Bradbury's countless creative endeavors. The result is the definitive story of how a great American author helped shape his times.

» Read more...

 

ANNOUNCEMENTS

IU and Regenstrief investigators honored by American Geriatrics Society

Michael LaMantia, M.D., MPH

Michael LaMantia, M.D., MPH

Indiana University Center for Aging Research and Regenstrief Institute investigators Michael LaMantia, M.D., MPH, and Kathleen Unroe, M.D., MHA, were honored by the American Geriatrics Society at its annual scientific meeting May 15 to 17.

Dr. LaMantia will receive an AGS New Investigator Award, one of only five to be presented by the national organization this year. This award honors individuals whose original research reflects new insights in geriatrics and a commitment to academics in aging.  He was previously honored by the AGS with a 2010 Annual Scientific Meeting Presidential Poster Award.

Dr. LaMantia focuses on the coordination of care for older, vulnerable patients as they transition across sites of health care delivery. He has a particular interest in the care of seniors in hospital emergency departments and especially the care provided there to seniors with dementia and delirium.

Delirium affects approximately 10 percent of older adults who seek care in the emergency department, yet it is unrecognized in the majority of cases. In 2014 Dr. LaMantia received a K23 award from the National Institute on Aging of the National Institutes of Health to support "DEEDS: Delirium Evaluation in the Emergency Department for Seniors." Also in 2014 he published an analysis of the problem in the Annals of Emergency Medicine.

» Read more...

IU School of Medicine Professor nabs digital media award for YouTube health program

Aaron Carroll, M.D.

Aaron Carroll, M.D.

An online video health program featuring IU School of Medicine's Aaron Carroll, M.D. received the inaugural Health Care Digital Media Award presented by the National Institute of Health Care Management Foundation.

The program, Healthcare Triage, is a YouTube channel in which Dr. Carroll, director of the IU Center for Health Policy and Professionalism Research, covers health care and health policy topics for general audiences.

In a breezy, quick-cut style, Dr. Carroll describes scientific studies and data, often using engaging graphics and everyday language to convey the information to lay audiences. Entries titled "Vaccines Don’t Cause Autism," "GMOs," "Doctors, Quality of Care, and Pay for Performance," and "Sometimes Faster is Better" were included in the awards submission.

"We want to translate data and evidence so that viewers can have a more sophisticated and rational discussion about policy," said Dr. Carroll, a pediatrician and associate dean for research mentoring at IU School of Medicine. "For example, in our submitted episodes we used systematic reviews and meta-analyses and individual studies to describe what is known, and how we might use evidence to move forward."

» Read more...

 

INSTITUTE SPOTLIGHT

Collaboration explores ways to personalize medicine

In cooperation with Eskenazi Health, the Indiana Institute for Personalized Medicine, the IU School of Medicine and the Regenstrief Institute are evaluating how genetics impact the responsiveness and efficacy of certain drugs. It is believed to be the first study of its kind to examine both the economic and clinical value of implementing personalized medicine.

Most medical treatments in use across the country today have been designed for the "average patient." As a result of this one-size-fits-all approach, treatments can be very successful for some patients but not for others. Taking into account individual differences in people's genes, environments and lifestyles, personalized medicine gives clinicians tools to better understand the complex mechanisms underlying a patient's health, disease or condition and to better predict which treatments will be most effective.

The groundbreaking study, launched at Eskenazi Health last month, will examine whether pharmacogenetic testing -- the study of the role of genetics in drug response -- is associated with improvements in clinical outcomes. In other words, the study will review whether information about a patient's genetic composition can be used to help guide a physician in determining what medications might be most effective for treating conditions such as hypertension, heart disease and diabetes. The study will target 33 drugs to also determine if there is significant association with a reduction in hospital and outpatient costs incurred over one year.

Lisa Harris, M.D.

Lisa Harris, M.D.

"For more than a century, our partnership with the Indiana University School of Medicine has helped to inform and advance how care is delivered across the world," said Lisa Harris, M.D., chief executive officer of Eskenazi Health. "The opportunity to now be on the leading edge of personalized medicine, with the precision that allows physicians and patients to more rapidly establish effective treatment and control of chronic conditions, is a direct result of our continued collaborative efforts to bring the best that science has to bear in improving care."

Lawmakers in Washington, D.C., are expected to consider a funding proposal from the White House later this year to invest millions of dollars in personalized medicine through research and translational sciences.

The two-year study at Eskenazi Health's main campus will enroll a total of 6,000 patients, with 2,000 patients assigned to a pharmacogenetic testing arm and 4,000 to a control arm of patients who will be followed, but not tested.

David Flockhart, M.D., Ph.D.

David Flockhart, M.D., Ph.D. | Photo By Indiana Institute for Personalized Medicine

Patients will be followed for one year. Eskenazi Health patients from both outpatient and inpatient areas of the health system as well as emergency department patients may be asked to participate if they are prescribed one of the 33 medications identified. Patients selected for the testing arm will receive a blood draw that will evaluate the most common type of genetic variations that exist within 16 specific genes. The blood draw is the only interaction patients will have with the study unless a second medication is prescribed during the course of the study period. David Flockhart, M.D., Ph.D., director of the Indiana Institute for Personalized Medicine and Paul Dexter, M.D., chief medical information officer at Eskenazi Health and Regenstrief scientist, are the study's principal investigators.

According to Dr. Flockhart, "Scientists will test the utility of this approach in a community-based setting, and in rural, underserved and economically disadvantaged populations and we need to figure out not only whether using genomics in the clinic can be helpful to patients, but also if it will be cost effective."

» Read more...

 

FACULTY SPOTLIGHT

The Genetic Portrait Project: Herron Professor documents people's perceptions of genetic research through photographs

Stefan Petranek

Stefan Petranek

Stefan Petranek, assistant professor of photography and intermedia at IUPUI’s Herron School of Art and Design, has taken an unusual approach to collecting people’s thoughts on science. With a marker and poster board in hand, Petranek asks individuals from a diverse range of backgrounds to consider “how the future will be affected by genetic research.” He then photographs his volunteers holding their message. In the last four years, Petranek has photographed over 400 individuals creating a noteworthy catalogue of responses that reflect the diversity of ethical concerns and technological promise this expansive field of science offers society.

As researchers’ ability to manipulate DNA for a wide array of biological issues, from human health to agricultural production advance, the influence of DNA-based technologies on our daily lives has grown exponentially. Yet there is little research which tracks Americans’ perceptions of these technologies. The Genetic Portrait Project grew out of Petranek’s ongoing artwork about the pyscho-social implications of a genetically advanced world and his interest in how others were grappling with the same issues. The project represents the first-ever visual documentary of individuals’ perceptions on science.

Stefan Petranek

American Society of Human Genetics (ASHG) Annual Meeting attendee looks at a sampling of Petranek's Genetic Portrait Project exhibit

Stefan Petranek

Petranek photographs subject for the Genetic Portrait Project

Petranek has photographed several high profile individuals for the project including Dr. Eric Green, Director of the National Human Genomic Research Institute at NIH, and internationally known artist, Mark Dion. He has also photographed individuals from a variety of backgrounds, including soliciting people off the streets from cities like Indianapolis, Boston, and Portland, OR to participate. Recently, Petranek has focused on creating interactive initiatives at genetic and bioethics conferences. In 2014, he photographed attendees at the American Society of Human Genetics (ASHG) Annual Meeting, the world’s largest genetics conference. His photographs have been exhibited nationally and were recently published in Frontline Genomic Magazine’s March issue. To see more portraits you can visit Petranek’s website and the Project’s Facebook page.

In the near future, Petranek plans to create a website that will allow people to participate autonomously, creating an international repository of photographic portraits dedicated to documenting thoughts on genetics at this moment in history.

 

STUDENT SPOTLIGHT

Herron grad's personal blog of 'Things Organized Neatly' takes international award

Webby Award Winner

Webby Award Winner

"Let me organize your things," said Austin Radcliffe, and with those five words the Herron School of Art and Design graduate accepted the 2015 People's Voice Webby Award for Personal Blog/Website during the 19th Annual Webby Awards on May 18.

Presented by the International Academy of Digital Arts and Sciences, the Webby Awards honors excellence on the Internet, in the categories of websites, advertising and media, online film and video, mobile sites and apps, and social. This year's 344 winners were chosen from nearly 13,000 entries from all 50 states and more than 60 countries.

Austin Radcliffe at work organizing things neatly

Austin Radcliffe at work organizing things neatly

Radcliffe's award-winning website, "Things Organized Neatly," includes images of just that -- things organized neatly -- created and curated by him.

His latest creation, "Springs Organized Neatly," was created specifically in celebration of his Webby award; the award logo and trophy are springs. The photo was shot in collaboration with Brooke Shanesy.

"Images on my blog come from artists, mainly photographers, all over the world," Radcliffe said. "I have featured approximately one photo every day for the last five years, so I couldn't have done it all myself. The site has become a documentation of the trend/style of organizing things neatly."

» Read more...

 

TRANSLATIONAL RESEARCH IMPACT

Researchers examine how to minimize drought impact on important food crops

Legumes

Legumes

The worldwide demand for legumes, one of the world’s most important agricultural food crops, is growing; at the same time, their production has been adversely affected by drought. In an IUPUI research paper published recently in the journal PLOS ONE, researchers provide information that could help agricultural planning and management to minimize drought-induced yield losses.

Legumes, which include peas, beans, peanuts and alfalfa, are grown in almost every climatic region and are second only to cereals in terms of contribution to food security.

World demand for legumes is expected to grow in the foreseeable future, not only in developing countries but also in the developed nations, given the trend toward healthy dieting. Frequent intake of legumes, which are rich in protein and soluble fiber, has been associated with reduction of cardiovascular diseases, diabetes, digestive tract disease and obesity. But many regions of the world have experienced significant shifts in the pattern and amount of rainfall, raising concerns about a growing water scarcity problem and increasing crop failure.

It has been unclear, however, how the effects of drought co-vary with legume species, soil condition, agroclimatic region and drought timing, said Lixin Wang, an assistant professor in the Department of Earth Sciences in the School of Science and the corresponding author of “Global synthesis of drought effects on food legume production.”

To address those uncertainties, the researchers collected literature data from 1980 to 2014 that reported legume yield responses to drought under field conditions, and they analyzed this large data set using meta-analysis techniques.

» Read more...

 

OVCR INTERNAL GRANT DEADLINES

Release Time for Research (RTR): IUPUI maintains a robust research enterprise. To support faculty with adequate time to prepare competitive proposals, the IUPUI Office of the Vice Chancellor for Research has developed the Release Time for Research (RTR) internal funding mechanism. This funding program allows IUPUI faculty a "buyout" of teaching time to prepare high-quality grant/contract proposals for submission to external funding agencies. It also supports non-tenure track faculty who are full-time senior lecturers or clinical track faculty possessing terminal degrees relevant to their fields, and who have a desire to engage in research or creative activity in an area that directly relates to their teaching or service mission. The next RTR application deadline is July 1, 2015. For grant guidelines and application forms, go to http://research.iupui.edu/funding/.

 

OTHER INTERNAL GRANT DEADLINES

Indiana CTSI seeks community-based research pilot projects

The Indiana Clinical and Translational Sciences Institute (CTSI) Community Health Engagement Program (CHEP) seeks proposals from applicants developing or currently involved in collaborative, community-based research projects. For this RFA, community-based research is a collaborative effort with at least one community-based organization and at least one academic partner.

The Indiana CTSI CHEP will provide up to $25,000 in funding per pilot project. Proposed project duration should not exceed 12 months. Focus areas of the 2015 RFA are in line with the priorities of the Indiana State Department of Health:

*Reducing infant mortality.

*Increasing immunizations.

*Decreasing tobacco use.

*Decreasing obesity.

Projects that propose achieving their objectives by changing or demonstrating the potential to change policy, systems and/or the environment are strongly encouraged.

Proposals are due by 5 p.m. July 21. For more information, the full Request for Applications is available. Frequently asked questions are also available.

 

EVENTS AND WORKSHOPS

Bioinformatics interns

As competition for external funding becomes more challenging, getting one's scholarly work successfully published is more important than ever. Dr. Gopen's approach is based on a single idea: learning to write for the reader allows the writer to control what readers learn.
This year, Dr. George Gopen will present this workshop on Tuesday, July 28. To register for the introduction workshop, click here.

Faculty who are planning to attend the advanced workshop on Wednesday, July 29 MUST attend the introduction workshop or have attended one in the years prior. To register for Wednesday, July 29, please click here.

As in past years, Dr. Gopen will also conduct hour-long, individualized consultations. ONLY faculty members who participate in the day-long event will have access to the individual consultation registration. Instructions will be sent to participants after their registration for the workshop is complete.

More about Dr. Gopen's original approach to scientific writing can be found in his article, The Science of Scientific Writing.

About the Presenter

George D. Gopen is a Duke University Emeritus Professor of the Practice of Rhetoric. He is also Senior Lecturing Fellow, Department of English and Senior Lecturing Fellow, School of Law. Professor Gopen received both his J.D. and his Ph.D. in English from Harvard University. Dr. Gopen is a pioneer in the mastery of scientific writing. His scientific clients have included the NIH, the FDA, Bristol-Myers Squib, Bayer, and Duke University School of Medicine.

This event is sponsored by the IU School of Medicine Office of Faculty Affairs and Professional Development, the IUPUI Office of the Vice Chancellor for Research and the IUPUI Center for Teaching and Learning.

Herron School of Art and Design’s 2015 Summer Exhibitions

The Herron School of Art and Design will feature works by five artists in a range of media from photography to painting to sculpture and video.

A reception in Eskenazi Hall on July 10 from 5:00 p.m. to 8:00 p.m. will open the galleries, which are free and open to the public. The exhibitions continue through July 31.

Michelle Given lives and works in Indianapolis and has taught at Murray State University as well as Indiana University. Her work in this show includes interior spaces, landscapes and cityscapes, and video.

Stacey M. Holloway, Herron alumna (B.F.A. 2006) and former faculty member, is an assistant professor of sculpture at the University of Alabama, Birmingham. Her cache of poignant yet whimsical dioramas sold out at a recent gallery show in New York, so she has promised to make new works for this exhibition.
Valerie Eickmeier, dean of Herron, will exhibit selected works created during her recent sabbatical that meld real experiences and observations with imagined and reinterpreted images.

These paintings are based on changing sequences in nature as well as contemplation of the underlying forces that create change. In the Marsh Gallery, recent works by Marianne Glick will be on display. The civic leader and philanthropist began painting in 2004 as she searched for a creative outlet to replace gardening during the winter. She describes herself as an abstract expressionist who works mostly in watercolor and acrylic. The Basile Gallery will feature works by R. Stephen Lehman. A prosthodontist by profession, Lehman began his love of photography in college shooting campus parties. He likens his seriousness about the medium to that of legendary cellist Pablo Casals, who was once asked why, at 93, he continued to practice three hours a day. Casals replied, “I’m beginning to notice some improvement.”

Hate Speech and the First Amendment: Values in Conflict

Date/Time: 06/19/2015, 12:00 pm - 1:00 pm
Location: Scottish Rite Cathedral (650 N Meridian Street) - Free
At what point, if at all, should so-called “hate speech” become illegal? During the monthly luncheon of the League of Women Voters ‎of Indianapolis, hear attorney and civic leader Don Knebel discuss hate speech and the First Amendment.

Can We Talk about RFRA without Talking Past One Another?

Date/Time: 6/24/2015, 6:00 pm - 7:30 pm
Location: IU Robert H. McKinney School of Law Wynne Courtroom (530 W. New York) – FREE (register at http://mckinneylaw.iu.edu/events/current.cfm?eid=346)
It’s fair to say that the controversy over RFRA raised more heat than light. This panel aims to model thoughtful conversation on the constitutional and philosophical questions raised by the RFRA debate. Hear from executive director of the ACLU of Indiana Jane Henegar, IU McKinney Professor of Law John Hill, and attorney and IBJ columnist Peter Rusthoven, with panel moderation by IU McKinney Professor of Law Robert Katz. 1.5 hours of CLE credit available.

 

RECENT EXTERNAL FUNDING AWARDS

The Office of the Vice Chancellor for Research recognizes and congratulates all IUPUI faculty and researchers for recent awards they have received and that help to advance the IUPUI research enterprise. The following table highlights those receiving $100,000 or more in external grants.

Grants and Awards – May 2015

PI Agency Project Title School Department Total

Yang, X Frank

NATIONAL INSTITUTE ALLERGY & INFECTIOUS DISEASES

Host adaptation of the Lyme disease spirochete

MEDICINE

MICROBIOLOGY & IMMUNOLOGY

     $2,062,342

Zimmers, Teresa Audrey

NATIONAL CANCER INSTITUTE

PQB3: Mechanisms & Targeting of Sonic Hedgehog Signaling in Muscle Wasting of Cancer Cachexia

MEDICINE

GENERAL SURGERY

     $1,432,067

Li, Lei

NATIONAL SCIENCE FOUNDATION

Mechanistic studies of the spore photoproduct lyase

SCIENCE

CHEMISTRY

        $650,000

Davis, Stephanie D

UNIVERSITY OF WESTERN AUSTRALIA

Identifying the clinical utility of MBW in early CF lung disease

MEDICINE

PED-PULM CRITICAL CARE/ALLERGY

        $259,605

Schrader, Stuart M

MARION COUNTY HEALTH DEPARTMENT

15-16  Marion County Public Health Department Professional Service Grant,  Ryan White Services Program: Oral Health Fee for Dental Service and Outreach Services

DENTISTRY

DENTISTRY-RESEARCH

        $156,959

Bodenhamer, David J

GEORGIA EMERGENCY MANAGEMENT AGENCY

Proposal to Develop Building Inventory Translators and Hazus Level II Risk Assessments for Selected Counties in Georgia

LIBERAL ARTS

POLIS

        $150,100

Logan, Theodore F.

YALE UNIVERSITY

Stand Up To Cancer Consortium Genomics-Enabled Medicine for  Melanoma (G.E.M.M.): Using Molecularly-Guided Therapy for Patients with  BRAF wild-type (BRAFwt) Metastatic Melanoma

MEDICINE

HEMATOLOGY/ONCOLOGY

        $119,845

Curtis, Edward E

NATIONAL ENDOWMENT FOR THE HUMANITIES

World Religions in Greater Indianapolis

LIBERAL ARTS

LIBERAL ARTS

        $119,009

Sankar, Uma

U.S. DEPARTMENT OF DEFENSE

CaMKK2 Inhibition in Enhancing Bone Fracture Healing

MEDICINE

ANATOMY & CELL BIOLOGY

        $101,762

Duman Scheel, Molly

BILL & MELINDA GATES FOUNDATION

Small Interfering RNA Larvicides for Control of Malaria Vector Mosquitoes

MEDICINE

IUSM-SOUTH BEND

        $100,000

 

CURRENT EXTERNAL FUNDING OPPORTUNITIES

Funding opportunities in this section include selected current grant announcements from federal agencies for new initiatives and changes to existing programs. Announcements with limited scope are not listed here but instead are sent directly to IUPUI School Deans. For comprehensive coverage of funding opportunities, please use the links to online search tools listed below.

GOOGLE

Google Research: Faculty Research Awards: This program aims to identify and support world-class, full-time faculty pursuing research in areas of mutual interest. The intent of the Awards is to support cutting-edge research in Computer Science, Engineering, and related fields. Applicants are asked to categorize their proposals into one of the following broad research areas of interest to the company: Computational neuroscience, Economics and market algorithms, Geo/maps, Human-computer interaction, Information retrieval, extraction, and organization (including semantic graphs), Machine learning and data mining, Machine perception, Machine translation, Natural language processing, Networking, Online education at scale, Physical interactions with devices, Policy and standards, Privacy, Robotics, Security, Social networks, Software engineering and programming languages, Structured data and database management, and Systems (hard/software).

Each funded project will be assigned a Google sponsor. The role of the sponsor is to support the project by discussing research directions, engaging with professors and students, and overseeing collaboration between the project team and Google. The company encourages Research Awards recipients to visit Google to give talks related to their work and meet with relevant research groups here. Through the Research Awards program, the company tries to fund projects where collaboration with Google will be especially valuable to the research team.
Deadline: October 15, 2015. http://research.google.com/university/relations/research_awards.html

General Motors Foundation

The General Motors Foundation supports only programs that fall within the Foundation's four key focus areas: education, health and human services, environment and energy, and community development. Primary consideration is given to requests that meet the following criteria:
1. Exhibit a clear purpose and defined need in one of the Foundation's four key focus areas.
2. Implement innovative approaches to address the defined need.
3. Demonstrate efficiency and the ability to follow through on the proposal.
Deadline: Continuous. http://www.gm.com/company/aboutGM/gm_foundation.html


NOTE:Faculty, researchers, and scientists interested in this funding opportunity may also consider pursuing a collaborative relationship that provides access to uniquedatafor appropriate research projects. This data has been collected from a broad spectrum of public safety personnel from various agencies in Indiana over the past two decades. Cardiovascular disease happens to be the primary cause of on-duty and lifetime mortality in firefighters (45% and 36% of deaths, respectively). Dataset includes: tobacco and alcohol use, diet, physical activity level, medications, immunization history, overall fitness, blood pressure, weight, lung function, blood analysis/lipids/glucose, urine analysis, psychological overview. Over 100,000 person-years are available.  Data is currently being accessed for FEMA/Homeland Security study through Harvard School of Public Health. (S. Kales, Primary Investigator). To learn more about this data and explore the feasibility of a joint project for this funding opportunity, please contact Terry Zollinger, Professor Emeritus, Fairbanks School of Public Health, at 317.278.0307 or tzolling@iu.edu).

NATIONAL INSTITUTES OF HEALTH

Developing the Therapeutic Potential of the Endocannabinoid System for Pain Treatment (R01): The purpose of this opportunity is to support projects that will elucidate the therapeutic potential of the cannabinoids and endocannabinoid system in the development of mechanism-based therapies for pain. Components of Participating Organizations: National Institute on Drug Abuse (NIDA), National Cancer Institute (NCI), National Institute on Aging (NIA), National Center for Complementary and Integrative Health (NCCIH), National Institute of Neurological Disorders and Stroke (NINDS), National Institute on Alcohol Abuse and Alcoholism (NIAAA), and the Eunice Kennedy Shriver National Institute of Child Health & Human Development.
Deadlines: AIDS related: September 7, 2015; all other: October 5, 2015. http://grants.nih.gov/grants/guide/pa-files/PA-15-188.html

High Throughput Screening (HTS) to Discover Chemical Probes (X01): This Resource Access Opportunity is to promote and support discovery and development of new chemical probes as research tools for use by the research community to advance the understanding of biological functions and disease mechanisms. The announcement encourages partnership between assay submitters and a funded High Throughput Screening (HTS)/chemical probe discovery facility to conduct the joint research. Through this announcement, NIH wishes to stimulate research in 1) discovery and development of novel, small molecules for their potential use in studying disease treatment relevant to the missions of the participating NIH Institutes and Centers, and 2) discovery and/or validation of novel, biological targets that will inform studies of disease mechanisms. Emphasis will be placed on assays that provide new insight into important disease targets and processes. Components of Participating Organizations: National Institute of Mental Health (NIMH), National Institute on Alcohol Abuse and Alcoholism (NIAAA), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institute on Drug Abuse (NIDA), and the National Center for Advancing Translational Sciences (NCATS).
Deadlines; Letters of Intent: 30 days before submission; Applications: August 5 & December 4, 2015. http://grants.nih.gov/grants/guide/pa-files/PAR-13-134.html

Obesity and Asthma: Awareness and Self-Management (R01): The purpose of this opportunity is to stimulate research to examine the relationship between asthma, obesity and self-management. The prevalence of both asthma and obesity has significantly risen in the past few decades. Although the association between these two conditions has been found in many studies, the exact mechanisms for how this association arises are unresolved to include self-management and to achieve control. Because both of these conditions have their beginnings in early life, an aspect of the association between them that requires more understanding is their common exposures in early life and transition into adulthood. Studies that investigate the molecular pathways linking asthma and obesity are encouraged as long as the studies describe how this relates to self-management. In addition, intervention studies targeting asthma or obesity and their effects on each other, and possible mechanisms of action and effect on behavior, are encouraged.
Deadline: October 5, 2015. http://grants.nih.gov/grants/guide/pa-files/PA-14-316.html

NATIONAL SCIENCE FOUNDATION

Quantum Information Science: Quantum Information Science (QIS) supports theoretical and experimental proposals that explore quantum applications to new computing paradigms or that foster interactions between physicists, mathematicians, and computer scientists that push the frontiers of quantum-based information, transmission, and manipulation. The quantum-based information science program is focused on investigations relevant to disciplines supported by the Physics Division, while encouraging broader impacts on other disciplines. Disciplines within the purview of the Physics Division include: atomic, molecular, optical, plasma, elementary particle, nuclear, gravitational and biological physics, particle astrophysics, and accelerator science.

Proposals with intellectual focus in areas supported by other NSF Divisions should be submitted to those divisions directly. Proposals that cross Divisional lines are welcome, but the Physics Division encourages PIs to request a co-review by naming other Divisional programs on the cover sheet. This facilitates the co-review and participation of other programs in the review process.
Deadline: December 3, 2015. http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=505207

Integrative Paleoanthropology Grants (IPG): The goal of this competition is to further innovative, integrative research to elucidate hominin biological and behavioral evolution. The particular focus is on long-term processes within hominin evolution and how they relate to major questions of paleoanthropological significance. While the intellectual scope of the competition is thus constrained, the potential methodologies and disciplines are not. It is understood, for example, that fields such as, but not limited to, cognitive science, genetics, and spatial or mathematical modeling may be directly relevant to such an endeavor. Competition organizers recognize that much paleoanthropological research is currently interdisciplinary and integrative in nature. However, the competition is intended to stimulate research that is integrative and crosses intellectual/disciplinary boundaries in novel ways, above and beyond current practice. As general examples, an integrative and interdisciplinary project might: 1) encompass broader perspectives, not previously synthesized, on regional and large-scale comparative issues, or 2) result in the development and application of an innovative method informed by multiple disciplines. Proposals are required to address this issue directly in the project description by using up to two pages of the 15 to specifically speak to how the proposed research is both integrative and novel beyond norms currently in practice and how the proposed research could not be accomplished otherwise. Reviewers and Program Officials will place significant weight on this criterion.
Deadline: April 2, 2015. http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=505181

Designing Materials to Revolutionize and Engineer our Future (DMREF): This program will support efforts that span researchers in materials science, chemistry, mathematics, computer science, and engineering, thereby bridging Program and Divisional interests. The complexity and challenge of activities addressed by this initiative require a transformative approach to discovering and developing new materials, predicting and optimizing properties of materials, and informing the design of material systems. Accordingly, the proposed research must be a collaborative and iterative process wherein theory guides computational simulation, computational simulation guides experiments, and experiments further guide theory. Strategies must be included in the proposed research to advance synthesis/growth/processing techniques, characterization/testing methodology, and theory/data/computation/simulation approaches needed to develop predictive models.

This process will require a team of PIs with the requisite expertise. Accordingly, it is expected that proposed projects will be directed by a team of at least two Senior Personnel with complementary expertise. The proposal must provide a plan for enhanced data management that ensures transparency, data sharing, and open source software, including an explicit statement of which open source license(s), if applicable, will be used. While not required, ties with industry, national laboratories, engineering partners, or other organizations are encouraged. If there are strong collaborations with industry, please see the Grant Opportunities for Academic Liaison with Industry (GOALI) program solicitation, which can be used in conjunction with this effort. Because this DMREF approach emphasizes an integrated approach to materials research, cross-disciplinary educational activities are encouraged, as are public outreach activities.
Deadline: January 29, 2016. http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=505073&org=NSF&sel_org=NSF&from=fund

U.S. DEPARTMENT OF DEFENSE (DOD)

Awards to Stimulate and Support Undergraduate Research Experiences (ASSURE):  The ASSURE program aims to provide valuable research opportunities for undergraduates, either through ongoing research programs or through projects specially designed for this purpose. Research projects should allow high quality interaction of students with faculty and/or other research mentors and access to appropriate facilities and professional development opportunities. Active research experience is considered one of the most effective ways to attract and retain talented undergraduates in science and engineering. ASSURE projects must have a well-defined common focus that enables a research-related experience for students. Applicants are encouraged to involve students in research who might not otherwise have the opportunity, particularly those from institutions where research programs are limited. Thus, a significant fraction of the student participants should come from outside the host institution. In addition, DoD is interested in strengthening institutions with limited research programs and especially encourages proposals that help to enhance the research infrastructure in predominantly undergraduate four-year institutions. Student participants must be citizens or permanent residents of the United States or its possessions. There is no separate application for the ASSURE program; ASSURE funding is awarded through the NSF REU Sites Program. Any proposal submitted to NSF for the REU Sites program that is recommended for funding through the NSF merit review process will be considered by DoD representatives for possible support through ASSURE.
Deadline: August 27, 2015. http://www.wpafb.af.mil/library/factsheets/factsheet.asp?id=9333


NOTE: All faculty, researchers, and scientists on continuing contracts at IU interested in applying for Department of Defense funding are eligible for assistance by the consulting firm Cornerstone Government Affairs as arranged by the Vice President for Research.  Those interested in securing assistance from Cornerstone must submit a two-page summary of their research project and a CV or biosketch to the VP for Research Office at vpr@iu.edu . Prior to submission, the IUPUI Office of the Vice Chancellor for Research is offering assistance with the two-page summaries. For more information, contact Ann Kratz at akratz@iupui.edu.

U.S. DEPARTMENT OF ENERGY (DOE)

Reliable Electricity Based on Electrochemical Systems (REBELS): This program seeks to disrupt traditional learning curves for distributed, stationary power generation by introducing technology concepts that have the potential for significantly lower cost and that are capable of performance superior to current distributed generation technologies. Fuel cell technologies have been touted for decades due to their high chemical-to-electrical conversion efficiencies and potential for near-zero greenhouse gas emissions when fueled by hydrogen or operated as part of a carbon capture and storage (CCS) process. However, fuel cell technologies have not achieved widespread adoption due primarily to high cost relative to incumbent combustion technologies. In this program, ARPA-E seeks to fund transformational fuel cell devices that operate in an intermediate temperature range in an attempt to 1) create new pathways to achieve an installed cost to the end-user of less than $1,500/kW at moderate production volumes, and 2) create new fuel cell functionality to increase grid stability and integration of renewable energy technologies such as wind and solar.
Deadline: Concept Paper: January 8, 2016. https://arpa-e-foa.energy.gov/#FoaId63d6bcce-92dc-4656-a650-1111825cfd42

 

IDENTIFYING FUNDING OPPORTUNITIES

On-line search tools are available to IUPUI investigators who are interested in identifying funding opportunities in their areas of interest.

Community of Science (COS): COS is a primary on-line search tool for identifying funding opportunities. To take advantage of this tool, register at http://www.cos.com/login/join.shtml. Once you have completed the short registration process, you can personalize your search by selecting the option entitled “launch your workbench”. You can access federal, local, corporate, foundation, nonprofit and other funding opportunities using key terms and save the results of up to 20 searches and have them delivered to you weekly via email.

National Institutes of Health (NIH) “NIH Guide”: To take advantage of this search tool, register at http://grants.nih.gov/grants/guide/listserv.htm. It allows you to receive discipline specific funding opportunities that are delivered to you weekly via email.

National Science Foundation (NSF) “MyNSF”:To take advantage of this search tool, register at http://service.govdelivery.com/service/multi_subscribe.html?
code=USNSF&custom_id=823
. It allows you to receive discipline specific funding opportunities that are delivered to you weekly via email.

Federal Business Opportunities “FedBizOpps”: FedBizOpps is the single government point-of-entry for Federal government procurement opportunities over $25,000. To take advantage of this search tool, visit https://www.fbo.gov. Opportunities found at this site include, but are not limited to, presolicitations and special notices for research and service contracts for specific projects and some national centers and surveys that would not be found in Grants.gov and may not be found in the Community of Science.

Limited Submission Funding Opportunities:

Many federal agencies and foundations offer grants, awards and fellowships that limit the number of applications that can come from one institution or require special handling. In order to comply with agency and foundation guidelines and increase the chances of Indiana University (IU) succeeding in such limited submissions and special handling opportunities, IU policies and procedures are in place and are utilized by the Office of the Vice Chancellor for Research and other IU research offices to facilitate internal coordination and competitions.

Individuals interested in responding to limited submission opportunities must inform the Office of the Vice Chancellor for Research about their intent to apply to a given limited submission opportunity, such that they can be included in the internal review and selection process. Failure to do so may disqualify individuals from consideration for submission to the funding opportunity.

Individuals interested in a limited submission opportunity or have any questions about the internal coordination process, contact Etta Ward at emward@iupui.edu or 317-278-8427. For a description of upcoming limited submission funding opportunities, as well as guidelines and application forms, go to: http://research.iu.edu/limited_sub.shtml. Please note that this is not a comprehensive list, and that any external funding opportunity that imposes any type of submission limitation is subject to the IU limited submission policy and procedures.

 

Office of the Vice Chancellor for Research - ovcr@iupui.edu
Indiana University Purdue University Indianapolis
755 West Michigan Street, UL1140, Indianapolis, IN 46202-2896
Phone: (317) 278-8427

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