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Research Enterprise Newsletter

The Office of the Vice Chancellor for Research (OVCR) publishes the RESEARCH ENTERPRISE to keep the academic community and the community at large informed about research activities, opportunities and development on the IUPUI campus.

Research Offices:
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Enterprise Archive


Editor:
Etta Ward

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Fred Haver


If you have a news item or recent noteworthy research-related achievement that you would like to share, please see the Research Enterprise Submission Guidelines.

Please be aware that not all news items will be deemed appropriate or timely for publication, but each item will be carefully considered.

April 24, 2015

INSIDE THIS ISSUE:

 

FEATURE STORY

IUPUI mathematician receives $1.4 million to study link between respiration and high blood pressure in sleep apnea

Yaroslav Molkov,Ph.D.

Yaroslav Molkov,Ph.D.

Yaroslav Molkov, assistant professor of mathematics in the School of Science at Indiana University-Purdue University Indianapolis, has received a $1.4 million grant from the National Institutes of Health to study the neuroscience underlying obstructive sleep apnea -- specifically targeting how respiration and high blood pressure are linked in the brain.

Sleep apnea affects an estimated 25 million adults in the United States and is associated with increased risk of hypertension, stroke, health attack and heart failure.

Obstructive sleep apnea is characterized by recurrent upper airway collapses resulting in brief interruptions of breathing during sleep. Episodes occur repeatedly. Untreated obstructive sleep apnea has cumulative effects on the cardiovascular system, leading to hypertension that may be drug resistant. It is estimated that half of all individuals with obstructive sleep apnea are hypertensive.

The five-year award (R01AT008632-01) from NIH's National Center for Complementary and Integrative Health will enable Molkov to develop a computational model to simulate the electrical signals generated by neurons that travel from the brain to the muscles controlling breathing and blood vessels.

» Read more...

 

ANNOUNCEMENTS

Successful 7th Annual Research Day Recap

Undergraduate student research, Darryl Watkins, explains his research to high school students

Undergraduate student research, Darryl Watkins, explains his research to high school students

Hosted by the Office of the Vice Chancellor for Research and the Center for Research and Learning, Research Day is an annual celebration of campus research and creative activity held at the Campus Center. And by all accounts, this year’s theme, "Research and Creative Activity . . . Fulfilling the Promise," did just that. It fulfilled the promises of showcasing some of the extraordinary work taking place on campus as well as offering an introduction to the world of research to over 800 attendees, including community members and local high school students.

Vice Chancellor for Research Kody Varahramyan opened the all-day event with welcoming remarks that highlighted the depth and breadth of campus research projects. He was followed by Stephan Viehweg, interim director of IUPUI Center for Translating Research Into Practice, who introduced this year’s Research Frontiers Trailblazer Award winners, a program that recognizes outstanding IUPUI researchers who show great promise in becoming renowned for their accomplishments. The three honorees for 2015 were Drs. Molly Duman Scheel (Associate Professor of Medical and Molecular Genetics), Yiqing Song (Associate Professor of Epidemiology), and Jian Xie (Associate Professor of Mechanical Engineering). The trio spoke on their work in mosquito biology and potential insecticides (Scheel), nutritional factors in type 2 diabetes and cardiovascular disease (Song), and nanomaterials for fuel cells and energy storage (Xie).

» Read more...

 

IUPUI announces 2015 Research Frontiers Trailblazer Award winners at 7th Annual Research Day

Established in 2010, the Research Frontiers Trailblazer Award recognizes outstanding IUPUI researchers who are showing great promise in becoming nationally and internationally known for their accomplishments in advancing the frontiers of knowledge. Specifically, the award is for outstanding accomplishments in research and creative activity by an associate professor within the first three years of promotion or appointment in the given rank.

Left to right: Dr. Jian  Xie, Dr. Molly Duman Scheel, Dr. Yiqing Song, and Dr. Kody Varahramyan (IUPUI Vice Chancellor for Research)

Left to right: Dr. Jian Xie, Dr. Molly Duman Scheel, Dr. Yiqing Song, and Dr. Kody Varahramyan (IUPUI Vice Chancellor for Research)

On April 17, the three winners of the 2014-15 Research Frontiers Trailblazer Awards received honors at IUPUI Research Day for their research on mosquito developmental genetics -- namely, Dr. Molly Duman Scheel, associate professor of medical and molecular genetics; the roles of nutritional factors on type 2 diabetes and cardiovascular disease – namely, Dr. Yiquing Song, associate professor of epidemiology; and on the development and use of nanostructured materials – namely, Dr. Jian Xie, associate professor of mechanical engineering. Each winner received a plaque and a $1000 cash prize.

» Read more...

 

CENTER SPOTLIGHT

Genetic markers may help determine who benefits from aspirin and/or NSAIDs in lowering colorectal cancer risk

Hongmei Nan, M.D., Ph.D.

Hongmei Nan, M.D., Ph.D.

An Indiana University cancer researcher and her colleagues have identified genetic markers that may help determine who benefits from regular use of aspirin and other nonsteroidal anti-inflammatory drugs for lowering one’s risk of developing colorectal cancer.

Previous studies have shown that regular use of aspirin and NSAIDs lower one’s risk of colorectal cancer, but their use is not recommended as a way to prevent the disease because of uncertainty about the risks and benefits. Thus, the researchers set out to examine the interrelationship between genetic markers and the use of aspirin and NSAIDs to learn who actually benefits from their use. They did so by conducting a genome-wide analysis of gene by environment interactions.

Hongmei Nan, M.D., Ph.D., research associate professor in the Department of Epidemiology at the Richard M. Fairbanks School of Public Health at IUPUI, and a researcher at the Indiana University Melvin and Bren Simon Cancer Center, along with her colleagues, found that colorectal cancer risk differed according to genetic variation at two single nucleotide polymorphisms -- more commonly known as SNPs -- at chromosomes 12 and 15. Interestingly, for the SNP at chromosome 12, they found that aspirin and/or NSAID use was associated with a lower risk of colorectal cancer among individuals with a specific genotype, while a higher risk was found among those with other genotypes.

Their study was published March 17 in the Journal of the American Medical Association.

» Read more...

 

FACULTY SPOTLIGHT

IUPUI mechanical engineering faculty member, students win ultra-light vehicle design challenge

Andres Tovar, Ph.D.

Andres Tovar, Ph.D.

A School of Engineering and Technology faculty member and his graduate students won the $60,000 grand prize in a competition to design a safe ultra-light vehicle.

The winning design, submitted by Andres Tovar, an assistant mechanical engineering professor, and the students, was selected from among more than 250 conceptual designs submitted in the LITECAR Challenge: Lightweighting Technologies Enabling Comprehensive Automotive Redesign. Their design was selected by a panel of experts in materials, crashworthiness, structures, manufacturing, and safety.

The competition, sponsored by Local Motors in partnership with the Advanced Research Projects Agency-Energy, was described as “setting up the challenge and letting the imagination begin” to develop innovative ideas by using novel material technologies, structural designs, energy-absorbing materials, and unique methods of manufacturing to reduce vehicle curb weight while maintaining current U.S. automotive safety standards.

Competition officials said the winning grand prize submission delivered “pretty much the entire package we were looking for,” by effectively creating an exoskeleton over an aluminum frame to protect vehicle occupants.

» Read more...

 

STUDENT SPOTLIGHT

Neuroscience student inspires IUPUI with research

Darryl Watkins | Undergraduate, Neuroscience

Darryl Watkins | Undergraduate, Neuroscience

For Darryl Watkins, a senior neuroscience major, being a non-traditional student does not mean missing out on any part of the IUPUI experience. Growing up in a single-parent home, “education was never really a priority for most of my family,” Watkins says.

Heavily involved in research, Watkins has excelled at IUPUI and was recently featured in the #InspireIUPUI campaign.

As a recipient of the Diversity Scholars Research Program (DSRP) scholarship and Undergraduate Research Opportunity Program (UROP) grant, Darryl participates in research with Feng C. Zhou, Ph.D., in the Department of Anatomy and Cell Biology at Indiana University School of Medicine. This opportunity has allowed Watkins the chance to create and run his own research project studying fetal alcohol syndrome in mice, under the guidance of Zhou.

“From conception, to planning, to the pitfalls, analyzing the data, and now writing the manuscript, I have been the only person on this project,” he said. “I believe it is this experience that has driven me to pursue a career in research. I continue because I truly believe this research will contribute to a much bigger story. Although this contribution may be small, it is nevertheless important.”

Watkin’s abstract for the research in Zhou’s lab, “Radiation Alters Epigenetic Programming in Young Adult Mice,” was selected for an oral presentation at the 2014 Louis Stokes Midwest Center for Excellence (LSMCE) conference, Roadmap to Action: LSAMP Model for Broadening Participation. As one of the top three submissions, Darryl received a monetary award to cover his travel expenses to the conference, October 25-26, 2014, in Chicago, IL. In addition, Watkins received Best Oral Presentation at the Indiana University Undergraduate Research Conference 2014 for his research.

Watkins encourages others to pursue their goals even if they seem out of reach at the time: “You can do it. I know this from experience now and all you have to do is believe you can do it.”

 

TRANSLATIONAL RESEARCH IMPACT

Researchers shaping care for older adults

The Center for Aging Research, affiliated with Regenstrief Institute, is based in the Health Information and Translational Sciences building near the downtown canal.

The Center for Aging Research, affiliated with Regenstrief Institute, is based in the Health Information and Translational Sciences building near the downtown canal.

In 1998, the IU School of Medicine launched the IU Center for Aging Research to help the university tackle health care issues faced by an aging population across the state and throughout the nation.

The center was established by director Chris Callahan, the Cornelius and Yvonne Pettinga Professor in Aging Research in the School of Medicine, whose game plan included consolidating IU’s emerging centers of excellence in the field.

“Our original mission was to be a research center for the care of older adults,” Callahan said. “We’ve stayed true to that mission, through partnerships and relationships that helped us help improve care, and better understand the emerging importance of self-care: the role older adults have in their own care.”

The relationships include long-standing ties to the Regenstrief Institute, Eskenazi Health (formerly Wishard Health), the medical school, and a growing research climate focused on geriatric care that has taken root in central Indiana.

» Read more...

 

OVCR INTERNAL GRANT DEADLINES

Release Time for Research (RTR): IUPUI maintains a robust research enterprise. To support faculty with adequate time to prepare competitive proposals, the IUPUI Office of the Vice Chancellor for Research has developed the Release Time for Research (RTR) internal funding mechanism. This funding program allows IUPUI faculty a "buyout" of teaching time to prepare high-quality grant/contract proposals for submission to external funding agencies. It also supports non-tenure track faculty who are full-time senior lecturers or clinical track faculty possessing terminal degrees relevant to their fields, and who have a desire to engage in research or creative activity in an area that directly relates to their teaching or service mission. The next RTR application deadline is July 1, 2015. For grant guidelines and application forms, go to http://research.iupui.edu/funding/.

 

OTHER INTERNAL GRANT DEADLINES

Indiana Diabetes Research Center Pilot and Feasibility Program applications due May 1

A primary research-related activity of the Indiana Diabetes Research Center Pilot and Feasibility Program is to foster the development of new diabetes-related investigators and provide seed support for innovative, high-risk projects. The pilot and feasibility program would like to fund three meritorious proposals, each requesting up to $25,000.

This funding opportunity is particularly directed to new investigators and established investigators new to diabetes-related research, and applications from investigators from the IU School of Medicine and IUPUI are encouraged. The program will also consider established diabetes investigators pursuing high-impact/high-risk projects or projects that are a significant departure from their usual work. IUSM and IUPUI are ideal for establishing interdisciplinary collaborations and forging new partnerships between basic scientists and clinical researchers, and such collaborations are encouraged.

Work supported by these funds is expected to lead to submissions of major extramural grants (R01/equivalent NIH, major foundation awards, DOD, etc.). New investigators must have no prior R01 funding, and all proposals must be directed towards basic biomedical, clinical, or translational research questions on cellular and molecular metabolism related to diabetes/obesity/metabolic syndrome, clinical and outcomes research in diabetes and obesity, complications of diabetes and obesity, islet function and survival, and/or nutrition and physiology of obesity.

Applicants should submit a letter of intent by 5 p.m. Wednesday, April 1. The deadline for applications is 5 p.m. Friday, May 1. The letters of intent and applications must be received via email at jelmendo@iupui.edu. For more information, visit the Indiana Diabetes Research Center's website or email jelmendo@iupui.edu.

 

OTHER EVENTS AND WORKSHOPS

Lecture: Dr. Stephen Selka presents "Mapping the Moral in African Diaspora Tourism in Brazil"

Target Audience: General
When: Friday, April 30, 2015 | 12:00pm - 1:30pm
Where: IUPUI Arts and Humanities Institute, University Library Room 4115S

This talk will explore African diaspora tourism in Bahia, Brazil, particularly African American “pilgrimages” to the Afro-Catholic festival of Our Lady of the Good Death (or simply Boa Morte) celebrated every August by women of African descent involved with the Afro-Brazilian religion of Candomblé. Although recognized as part of the official heritage of Bahia, Boa Morte occupies a complicated position on the Afro-Brazilian moral landscape. To evangelical Christians, for example, Boa Morte and Candomblé are diabolical; from this perspective, Afro-Brazilian religion is something to leave behind. By contrast, to the extent that the festival of Boa Morte is understood as a celebration honoring the ancestors, it is particularly appealing to African Americans seeking to “recover” their ancestral past. Nevertheless, ancestors are understood to be dangerous and morally unpredictable in Candomblé; therefore, Boa Morte is something morally ambiguous for many Candomblé practitioners, contrary to what most African American visitors might expect. Accordingly, this talk focuses on the contested links between heritage, personhood, and morality that are enacted at the festival of Boa Morte.

Stephen Selka is Associate Professor of Religious Studies and American Studies at Indiana University Bloomington. A cultural anthropologist, he researches religion, politics, and cultural heritage tourism in Afro-Brazilian communities in northeastern Brazil, where he has conducted ethnographic fieldwork since 1999. His first book, Religion and the Politics of Ethnic Identity in Bahia, Brazil (University Press of Florida, 2007), explores the various ways that Afro-Brazilians in both Christian and African-derived religious communities construct their ethnic identities and struggle against racism.

This public program is part of the Religion and Ethics Roundtables series of the IU Consortium for the Study of Religion, Ethics, and Society. Religion and Ethics Roundtables highlight the work of scholars at IUB, IUPUI, and beyond, with the goal of engaging the IU community and the public in dialogue about important issues at the intersection of religion, ethics, and society.

 

IUPUI Arts and Humanities Institute (IAHI) Spring 2015 Lineup

For details and to register, visit http://www.iupui.edu/~iahi/?page_id=39.

 

RECENT EXTERNAL FUNDING AWARDS

The Office of the Vice Chancellor for Research recognizes and congratulates all IUPUI faculty and researchers for recent awards they have received and that help to advance the IUPUI research enterprise. The following table highlights those receiving $100,000 or more in external grants.

Grants and Awards - March 2015

PI Agency Project Title School Department Total

Yu, Andy Qigui

NATIONAL INSTITUTE ALLERGY & INFECTIOUS DISEASES

Targeting latently infected Tfh cells to achieving a functional cure of HIV-1

MEDICINE

MICROBIOLOGY & IMMUNOLOGY

$1,930,382

Bell, Richard L

NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM

Preclinical Medications Screening in P and HAD Rats

MEDICINE

PSYCHIATRY

$1,816,475

Molkov, Yaroslav

NATIONAL CENTER FOR COMPLEMENTARY AND INTEGRATIVE HEALTH

Modeling the respiratory-sympathetic coupling in neurogenic hypertension

SCIENCE

MATHEMATICS

$1,354,853

Loehrer, Patrick J.

ELI LILLY AND COMPANY FOUNDATION

AMPATH Oncology Institute

MEDICINE

CANCER CENTER

$1,000,000

Wiehe, Sarah Elizabeth

AGENCY FOR HEALTHCARE RESEARCH AND QUALITY

Identifying Opportunities to Reduce STI/HIV Disparities among Recent Offenders

MEDICINE

PED-HEALTH SERVICES RESEARCH

$995,886

Buyarski, Catherine A

INDIANA COMMISSION FOR HIGHER EDUCATION

Supporting Student Persistence

UNIVERSITY COLLEGE

UNDERGRAD ED

$206,573

Ironside, Pamela M

THE ROBERT WOOD JOHNSON FOUNDATION

Planning the Nursing Education Research Network

NURSING

NURSING

$159,982

Brown, Cynthia Diane

CYSTIC FIBROSIS FOUNDATION

CFF Second Year Fellow

MEDICINE

PULMONARY

$127,500

McKinley, Todd Owen

JOHNS HOPKINS UNIVERSITY

The Major Extremity Trauma Research Consortium - METRC 2

MEDICINE

ORTHOPAEDIC SURGERY

$120,346

Harris, Tara L

INDIANA CRIMINAL JUSTICE INSTITUTE

Pediatric Center of Hope

MEDICINE

PED-CHILD PROTECTION PROGRAM

$106,626

Zhang, Shanxiang

INDIANA UNIVERSITY HEALTH

Identification of miRNAs for a unique subset of diffuse large B-cell lymphoma with better prognosis

MEDICINE

PATHOLOGY AND LABORATORY MED

$100,000

Kubal, Chandrashekhar Avinash

INDIANA UNIVERSITY HEALTH

 

MEDICINE

TRANSPLANT SURGERY

$618,311

 

CURRENT EXTERNAL FUNDING OPPORTUNITIES

Funding opportunities in this section include selected current grant announcements from federal agencies for new initiatives and changes to existing programs. Announcements with limited scope are not listed here but instead are sent directly to IUPUI School Deans. For comprehensive coverage of funding opportunities, please use the links to online search tools listed below.

U.S. DEPARTMENT OF DEFENSE (DOD)

Amyotrophic Lateral Sclerosis Research Program (ALSRP) Therapeutic Development Award: This opportunity supports the preclinical assessment of therapeutics for ALS. The proposed studies are expected to be empirical in nature and product-driven but may have a hypothesis-driven approach, provided the focus is on therapeutics. It is anticipated that the agents and/or data generated from these awards will lead to the advancement of new therapies for ALS. The FY15 award supports a wide range of post-discovery development activities ranging from post-discovery validation right up to IND submission. Supported activities must begin with lead compounds in hand and can include (1) secondary validation of leads obtained from screening or by other means to demonstrate target selectivity and mechanism of action, (2) optimization of potency and pharmacological properties and development of structure-activity maps via synthesis and testing of derivatives and sister compounds, (3) studies of formulation and stability, and/or (4) development of GMP production methods, (5) collection of data needed for Food and Drug Administration (FDA) Investigational New Drug (IND) applications to include compound characterization, absorption, distribution, metabolism, excretion (ADME) studies, and dose/response and toxicology studies. Deadlines: Pre-Application: May 11, 2015; Application: August 20, 2015.


NOTE: All faculty, researchers, and scientists on continuing contracts at IU interested in applying for Department of Defense funding are eligible for assistance by the consulting firm Cornerstone Government Affairs, as arranged by the Vice President for Research.  Those interested in securing assistance from Cornerstone must submit a two-page summary of their research project and a CV or biosketch to the VP for Research Office at vpr@iu.edu . Prior to submission, the IUPUI Office of the Vice Chancellor for Research is offering assistance with the two-page summaries. For more information, contact Ann Kratz, akratz@iupui.edu.

 

U.S. DEPARTMENT OF ENERGY (DOE)

Reliable Electricity Based on ELectrochemical Systems (REBELS)This program seeks to disrupt traditional learning curves for distributed stationary power generation by introducing technology concepts that have the potential for significantly lower cost and that are capable of performance superior to current distributed generation technologies. Fuel cell technologies have been touted for decades due to their high chemical-to-electrical conversion efficiencies and potential for near-zero greenhouse gas emissions when fueled by hydrogen or operated as part of a carbon capture and storage (CCS) process. However, fuel cell technologies have not achieved widespread adoption due primarily to high cost relative to incumbent combustion technologies. In this program, ARPA-E seeks to fund transformational fuel cell devices that operate in an intermediate temperature range in an attempt to 1) create new pathways to achieve an installed cost to the end-user of less than $1,500/kW at moderate production volumes, and 2) create new fuel cell functionality to increase grid stability and integration of renewable energy technologies such as wind and solar. Deadline: Concept Paper: January 8, 2016.

Stewardship Science Academic Alliances (SSAA)This program supports state-of-the-art research at U.S. institutions in areas of fundamental physical science and technology of relevance to the Stockpile Stewardship Program mission, with a focus on those areas not supported by other federal agencies. This opportunity seeks proposals in properties of materials under extreme conditions and/or hydrodynamics (condensed matter physics and materials science, and fluid dynamics); low energy nuclear science; and radiochemistry. The program objectives are: 1) Support the U.S. scientific community by funding research projects at universities that conduct fundamental science and technology research that is of relevance to Stockpile Stewardship; 2) Provide opportunities for intellectual challenge and collaboration by promoting scientific interactions between the academic community and scientists at the DOE/NNSA laboratories; and 3) Develop and maintain a long-term recruiting pipeline to the DOE/NNSA laboratories by training and educating the next generation of scientists in the fundamental research of relevance to Stockpile Stewardship and thereby increasing the visibility of the DOE/NNSA scientific activities to the U.S. academic communities. Deadline: October 27, 2015.

 

General Motors Foundation

The General Motors Foundation supports only programs that fall within the foundation's four key focus areas: education, health and human services, environment and energy and community development. Primary consideration is given to requests that meet the following criteria:
1. Exhibit a clear purpose and defined need in one of the foundation's four key focus areas.
2. Implement innovative approaches to address the defined need.
3. Demonstrate efficiency and the ability to follow through on the proposal.
Deadline: Continuous. http://www.gm.com/company/aboutGM/gm_foundation.html

NOTE:Faculty, researchers, and scientists interested in this funding opportunity may also consider pursuing a collaborative relationship that provides access to uniquedatafor appropriate research projects. This data has been collected from a broad spectrum of public safety personnel from various agencies in Indiana over the past two decades. Cardiovascular disease happens to be the primary cause of on-duty and lifetime mortality in firefighters (45% and 36% of deaths, respectively). Dataset includes: tobacco and alcohol use, diet, physical activity level, medications, immunization history, overall fitness, blood pressure, weight, lung function, blood analysis/lipids/glucose, urine analysis, psychological overview. Over 100,000 person years available.  Data is currently being accessed for FEMA/Homeland Security study through Harvard School of Public Health. (S. Kales, Primary Investigator). To learn more about this data and explore the feasibility of a joint project for this funding opportunity, please contact Terry Zollinger , Professor Emeritus, Fairbanks School of Public Health, 317.278.0307 or tzolling@iu.edu).

 

NATIONAL INSTITUTES OF HEALTH

Role of Exosomes in HIV Neuropathogenesis (R01): This opportunity invites research grant applications focused on defining the central role of exosomes in the neuropathogenesis of Human Immunodeficiency Virus (HIV)-1 Associated Neurocognitive Disorders (HAND) and determining the potential use of exosomes as biomarkers for HAND or as delivery vehicles for CNS-targeted therapeutics. Basic and translational research in domestic and international settings is of interest. Multidisciplinary research teams and collaborative alliances are encouraged but not required. Components of Participating Organizations: National Institute of Mental Health (NIMH) and National Institute of Neurological Disorders and Stroke (NINDS). Deadlines: Letter of Intent: August 2, 2015; Application: September 2, 2015.

Research Projects to Enhance Applicability of Mouse Models for Translational Research (R01): The purpose of this opportunity is to invite applications for projects to expand and improve the utility of mouse cancer and tumor models for translational research. The National Cancer Institute (NCI) supports many hypothesis-driven, mechanistic R01 projects that employ mice, or develop and use mouse cancer models or human-in-mouse tumor models for many aspects of oncology research. However, the NCI has not previously supported projects devoted to ensuring that mice and mouse models used for translational research questions are appropriate for those purposes and that the models provide reliable and informative data for patient benefit. Applications to this FOA could propose to overcome limitations of mouse and human-in-mouse oncology models, define a new translational use of models or mouse genetics for unmet needs, advance standard practices for modeling human cancers and tumors in mice and for validating and credentialing models, or develop widely applicable tool strains or resources that enable cross-species comparisons. Deadline: June 5, 2015.

NIH Transformative Awards (R01): The NIH Transformative Research Awards complement NIH's traditional, investigator-initiated grant programs by supporting individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. Little or no preliminary data are expected. Projects must clearly demonstrate the potential to produce a major impact in a broad area of biomedical or behavioral research. Deadlines: Letter of Intent: September 10, 2015; Application: October 10, 2015.

Technologies for Improving Health and Eliminating Health Disparities (R41/42): The purpose of this opportunity is to stimulate a partnership of ideas and technologies between innovative small business concerns (SBCs) and non-profit research institutions resulting in improving minority health and the reduction of health disparities by commercializing innovative technologies. Healthy People 2020 defines a health disparity as a particular type of health difference in the incidence, prevalence, morbidity, and burden of diseases and other adverse health outcomes that is closely linked with social, economic, and/or environmental disadvantage. NIH-defined health disparity population groups include racial/ethnic minorities, socioeconomically disadvantaged individuals, and individuals residing in rural areas. Appropriate technologies must be effective, affordable, culturally acceptable, and easily accessible to those who need them. Deadlines: Letter of Intent: December 23, 2015; Application: January 23, 2016.

 

NATIONAL SCIENCE FOUNDATION

Improving Undergraduate STEM Education (IUSE-EHR): This program invites proposals that address immediate challenges and opportunities that are facing undergraduate STEM education, as well as those that anticipate new structures (e.g. organizational changes, new methods for certification, course re-conception, cyberlearning, etc.) and new functions of the undergraduate learning and teaching enterprise. The IUSE program recognizes and respects the variety of discipline-specific challenges and opportunities facing STEM faculty as they strive to incorporate results from educational research into classroom practice and work with education research colleagues and social science learning scholars to advance our understanding of effective teaching and learning. The program features two tracks: 1)Engaged Student Learning and 2) Institutional and Community Transformation. Two tiers of projects exist within each track: (i) Exploration and (ii) Design and Development. These tracks will entertain research studies in all areas. In addition, IUSE also offers support for a variety of focused innovative projects that seek to identify future opportunities and challenges facing the undergraduate STEM education enterprise. Deadline: October 22, 2015.

Critical Resilient Interdependent Infrastructure Systems and Processes (CRISP): This opportunity seeks proposals with transformative ideas that will ensure ICI services are effective, efficient, dependable, adaptable, resilient, safe, and secure. Successful proposals are expected to study multiple infrastructures focusing on them as interdependent systems that deliver services, enabling a new interdisciplinary paradigm in infrastructure research. Projects may undertake the collection of new data or use existing curated data depending on the category of award, and must recognize that a primary objective is integrative, predictive modeling that can use the data to validate the models and that can be integrated into decision making. Type 1 Awards: Theory, modeling, data collection and metrics projects that will create the knowledge, representations, methodologies, case studies and approaches to conceptualize and study interdependent infrastructures as processes, services and systems. Type 2 Awards: These proposals support interdisciplinary research to conduct major new interdependent infrastructure research using empirical data. They are expected to include the creation of knowledge, representations, methodologies and approaches to conceptualize and study interdependent infrastructures as processes, services and systems. Deadline: March 20, 2016.

Interdisciplinary Behavioral and Social Science Research (IBSS): This opportunity invites proposals for two different kinds of projects: 1) IBSS Large Interdisciplinary Research Projects - Large interdisciplinary research projects. 2) IBSS Interdisciplinary Team Exploratory Projects - Support for exploratory efforts by emerging multidisciplinary teams is designed to facilitate the kinds of contact, interaction, and active research activities necessary to enable researchers from multiple disciplines to engage in effective interdisciplinary research. Emphasis is to be placed on the conduct of research and potential outcomes, not on the preparation of plans and proposals for future research. Projects may address any topic, issue, or problem. Researchers are encouraged to pursue research on one of four cross-cutting themes (population change; sources of disparities; communication, language, and linguistics; and technology, new media, and social networks), but the IBSS competition will be open and receptive to other topics that address topics having theoretical and societal significance. Proposals should focus on basic research projects. Development of new methods, collection of new databases of broader value, engagement in education and training activities, and/or other forms of infrastructural activity may be a part of the project's activities, but the project's primary emphasis should be on scientifically exploring the validity of answers to focused, theoretically-based questions. Deadline: December 2, 2015.

Campus Cyberinfrastructure: Data, Networking, and Innovation Program (CC*DNI): The CC*DNI program invests in campus-level data and networking infrastructure and integration activities tied to achieving higher levels of performance, reliability and predictability for science applications and distributed research projects. Science-driven requirements are the primary motivation for any proposed activity. The CC*DNI program welcomes proposals in seven areas: (1) Data Infrastructure Building Blocks (DIBBs) - Multi-Campus/Multi-Institution Model Implementations; (2) Data Driven Networking Infrastructure for the Campus and Researcher; (3) Network Design and Implementation for Small Institutions; (4) Network Integration and Applied Innovation; (5) Campus CI Engineer; (6) Regional Coordination and Partnership in Advanced Networking; and (7) Instrument Networking. Participating NSF organizations: Division of Advanced Cyberinfrastructure (ACI) and Division of Computer and Network Systems (CNS) in the Directorate for Computer & Information Science & Engineering (CISE). Deadline: March 26, 2016.

 

U.S. DEPARTMENT OF ENERGY (DOE)

Stewardship Science Academic Alliances (SSAA)This program supports state-of-the-art research at U.S. institutions in areas of fundamental physical science and technology of relevance to the Stockpile Stewardship Program mission, with a focus on those areas not supported by other federal agencies. This opportunity seeks proposals in properties of materials under extreme conditions and/or hydrodynamics (condensed matter physics and materials science, and fluid dynamics); low energy nuclear science; and radiochemistry. The program objectives are: 1) Support the U.S. scientific community by funding research projects at universities that conduct fundamental science and technology research that is of relevance to Stockpile Stewardship; 2) Provide opportunities for intellectual challenge and collaboration by promoting scientific interactions between the academic community and scientists at the DOE/NNSA laboratories; and 3) Develop and maintain a long-term recruiting pipeline to the DOE/NNSA laboratories by training and educating the next generation of scientists in the fundamental research of relevance to Stockpile Stewardship and thereby increasing the visibility of the DOE/NNSA scientific activities to the U.S. academic communities. Deadline: October 27, 2015.

 

U.S. DEPARTMENT OF TRANSPORTATION (DOT)

Strategies for Increasing Ignition Interlock Use Among DWI OffendersThe main objective of this opportunity is to measure the effectiveness of a strategy in increasing interlock use as deployed by a jurisdictional site (State, county, court system). The contractor shall gather information on interlock programs across a range of sites to identify and recruit a site that is willing or about to deploy a strategy for increasing interlock use. The contractor shall partner with a site and assess changes in program measures of performance prior to, during and after the strategy is deployed. Deadline: July 23, 2015.

 

IDENTIFYING FUNDING OPPORTUNITIES

On-line search tools are available to IUPUI investigators who are interested in identifying funding opportunities in their areas of interest.

Community of Science (COS): COS is a primary on-line search tool for identifying funding opportunities. To take advantage of this tool, register at http://www.cos.com/login/join.shtml. Once you have completed the short registration process, you can personalize your search by selecting the option entitled “launch your workbench”. You can access federal, local, corporate, foundation, nonprofit and other funding opportunities using key terms and save the results of up to 20 searches and have them delivered to you weekly via email.

National Institutes of Health (NIH) “NIH Guide”: To take advantage of this search tool, register at http://grants.nih.gov/grants/guide/listserv.htm. It allows you to receive discipline specific funding opportunities that are delivered to you weekly via email.

National Science Foundation (NSF) “MyNSF”:To take advantage of this search tool, register at http://service.govdelivery.com/service/multi_subscribe.html?
code=USNSF&custom_id=823
. It allows you to receive discipline specific funding opportunities that are delivered to you weekly via email.

Federal Business Opportunities “FedBizOpps”: FedBizOpps is the single government point-of-entry for Federal government procurement opportunities over $25,000. To take advantage of this search tool, visit https://www.fbo.gov. Opportunities found at this site include, but are not limited to, presolicitations and special notices for research and service contracts for specific projects and some national centers and surveys that would not be found in Grants.gov and may not be found in the Community of Science.

Limited Submission Funding Opportunities:

Many federal agencies and foundations offer grants, awards and fellowships that limit the number of applications that can come from one institution or require special handling. In order to comply with agency and foundation guidelines and increase the chances of Indiana University (IU) succeeding in such limited submissions and special handling opportunities, IU policies and procedures are in place and are utilized by the Office of the Vice Chancellor for Research and other IU research offices to facilitate internal coordination and competitions.

Individuals interested in responding to limited submission opportunities must inform the Office of the Vice Chancellor for Research about their intent to apply to a given limited submission opportunity, such that they can be included in the internal review and selection process. Failure to do so may disqualify individuals from consideration for submission to the funding opportunity.

Individuals interested in a limited submission opportunity or have any questions about the internal coordination process, contact Etta Ward at emward@iupui.edu or 317-278-8427. For a description of upcoming limited submission funding opportunities, as well as guidelines and application forms, go to: http://research.iu.edu/limited_sub.shtml. Please note that this is not a comprehensive list, and that any external funding opportunity that imposes any type of submission limitation is subject to the IU limited submission policy and procedures.

 

Office of the Vice Chancellor for Research - ovcr@iupui.edu
Indiana University Purdue University Indianapolis
755 West Michigan Street, UL1140, Indianapolis, IN 46202-2896
Phone: (317) 278-8427

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