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Research Enterprise Newsletter

The Office of the Vice Chancellor for Research (OVCR) publishes the RESEARCH ENTERPRISE to keep the academic community and the community at large informed about research activities, opportunities and development on the IUPUI campus.

Research Offices:
Enterprise Archive

Etta Ward

Fred Haver

If you have a news item or recent noteworthy research-related achievement that you would like to share, please see the Research Enterprise Submission Guidelines.

Please be aware that not all news items will be deemed appropriate or timely for publication, but each item will be carefully considered.

September 10, 2015



Message from the Vice Chancellor for Research

Vice Chancellor Simon Atkinson

Vice Chancellor Simon Atkinson

Dear Colleagues:

Welcome to the first edition of the Research Enterprise for the 2015-16 academic year. Research Enterprise is your first stop for information essential to your research, scholarship and creative activity, and the place to find out about the latest work from the vibrant community of students, staff and faculty at IUPUI.

This is an exciting time at IUPUI, with new campus leadership and big plans for research across all campuses of Indiana University. Here at IUPUI, we look forward to the start of the university’s Grand Challenges Initiative, which will launch a series of big and bold projects intended to transform the university and connect our researchers, scholars and artists to our community. To learn more about IU Grand Challenges program, visit This is a transformative opportunity for IUPUI faculty to engage in this strategic effort to change the university and have a meaningful impact around the state and beyond.

I encourage you to use the resources available to you through the Office of the Vice Chancellor for Research, whether it is our internal funding mechanisms, proposal development services or assistance with research commercialization. And we need your input too, so we can provide the services you need in a way that’s easy for you to access.

I wish you a successful and rewarding year, and look forward to learning about your achievements.

Simon Atkinson

Vice Chancellor for Research



IUPUI to collaborate with Purdue, State as part of $171 million FlexTech manufacturing initiative

IUPUI's FlexTech team

IUPUI's FlexTech team: Left to right - Mangilal Agarwal, directs the Integrated Nanosystems Development Institute and is Associate Director of Research Development at the Office of Vice Chancellor for Research, Jong Ryu, Assistant Professor of Mechanical Engineering in the School of Engineering and Technology and Research Member of Integrated Nanosystems Development Institute, Razi Nalim, Professor of Mechanical Engineering and Associate Dean for Research in the School of Engineering and Technology, and Clayton Nicolas, Industry Research Development Specialist, School Of Engineering and Technology and Office of the Vice Chancellor for Research

Researchers from Indiana University-Purdue University Indianapolis and Purdue University have been selected to co-lead a $13 million Indiana node of a U.S. Department of Defense-funded initiative to develop electronics and sensors that flex and stretch. Flexible hybrid electronics enable the integration of thin silicon electronic devices, sensors, communications and power on flexible substrates like glass, plastic, paper and human skin. Thinner wristwatches, personalized prosthetics, and more reliable robots and visual displays are among possible applications of the technology.

The defense department announced Aug. 28 that it had selected a proposal by FlexTech to establish and manage a flexible hybrid electronics manufacturing initiative. It is part of the National Network for Manufacturing Innovation program, an initiative of the Obama Administration to support advanced manufacturing in the U.S.

A research consortium and trade association based in San Jose, Calif., FlexTech is partnering with IUPUI, Purdue, the state of Indiana and other organizations. Overall funding amounts to $171 million: $75 million from federal sources over five years matched by more than $96 million in cost sharing from non-federal partners.

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Optimal exercise regimen could aid pulmonary hypertension patients

Mary Beth Brown

Mary Beth Brown

A physical therapy researcher with the IU School of Health and Rehabilitation Sciences at Indiana University-Purdue University Indianapolis has been awarded a $465,000 National Institutes of Health grant to optimize aerobic exercise training for patients with pulmonary arterial hypertension -- a goal that data suggests could reduce patient morbidity and mortality.

“Traditionally, it had been thought that these patients, who often struggle to walk across a room or climb a flight of stairs, shouldn’t exercise,” said Mary Beth Brown, an assistant professor in the Department of Physical Therapy.

“It’s only in the last decade that the first evidence came out that exercise may be OK and may even be beneficial,” Brown said. “Because it is such a relatively new potential therapy, there is a lot of work that needs to be done to optimize it, just like with any other new therapy.”

Pulmonary hypertension is high blood pressure that occurs in the arteries in the lungs. Blood vessels that carry blood from the heart to the lungs become narrow, forcing the heart to work harder to pump the blood through. As the pressure builds, the heart's right ventricle must work harder to pump blood through the lungs, eventually causing the heart muscle to weaken and eventually fail.

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Call for Nominations – Innovation-to-Enterprise Award for Research Commercialization

The Vice Chancellor for Research invites nominations for the 2015 Innovation-to-Enterprise Award. Faculty and staff researchers from any school of the Indianapolis campus are eligible. The award recognizes significant accomplishments in support of research commercialization, contributing to economic development, and social advancement. The award recipient will be recognized at the Innovation-to Enterprise Forum and Showcase on November 4, 2015. The deadline for nominations is October 2, 2015.

For more details on submission of nominations please visit the OVCR website (

Indiana University recognizes 10 years of New Frontiers in the Arts and Humanities funding

Indiana University's New Frontiers in the Arts & Humanities
Indiana University's New Frontiers in the Arts & Humanities

"This retrospective is an effort not just to summarize the New Frontiers program, but also to highlight the extraordinary achievements of our artists and scholars." -- IU Vice President for Research Fred H. Cate | Photos by Anila Quayyum Agha, Elizabeth Shea, Jeffrey Wolin

Reiko Toyama, Ph.D.

With "Labyrinths," Jeffrey Hass creates a space of free movement for IU graduate Kate Anderson within a 3-D maze. | Photo by Jeffrey Hass

Over 450 artists, scholars share the creative experience through their collective body of work: books, artwork, film, dance, and more.

One of Indiana University’s most prominent efforts to strengthen its long-standing commitment to excellence in the arts and humanities has been the university’s New Frontiers in the Arts and Humanities seed funding program. Initiated in 2004 with the generous support of a Lilly Endowment Inc. grant to promote excellence in Indiana, and subsequently renewed by IU President Michael A. McRobbie, New Frontiers has provided over $9.4 million to artists and humanities scholars at IU’s eight campuses.

Now, IU's Office of the Vice President for Research, which manages the New Frontiers program, and IU Communications in the Office of the Vice President for Engagement have created a multimedia retrospective that looks at the work of nearly fifty of those New Frontiers grant recipients, and at the broader, positive impacts of the program.

“New Frontiers both reflects and has contributed significantly to maintaining the vital role of the arts and humanities here at Indiana University,” said IU Vice President for Research Fred H. Cate.

“Over the past decade we at IU, throughout the State of Indiana and quite literally around the world have been the beneficiaries of the fruits of that commitment -- from operas and gallery shows, to award-winning books and internationally-recognized art installations,” Cate said. “This retrospective is an effort not just to summarize the New Frontiers program but also to highlight the extraordinary achievements of our artists and scholars.”

The New Frontiers program is designed to assist artists and humanities scholars in one of four ways:

*Produce innovative works of scholarship and creative activities.

*Provide the seed funding needed for them to venture into new trajectories of work.

*Fund academic events hosting major distinguished thinkers.

*Support national and international travel in pursuit of new, innovative projects.

The retrospective offers a variety of photographs, images and, audio and video files, along with hyperlinks to numerous New Frontiers grant winners and their works. In total, more than 450 IU faculty members have been supported by New Frontiers funding. The retrospective identifies how those scholars and artists were able to better support students, earn additional external funding and successfully conduct community outreach while also producing innovative works of art and scholarship.

In December 2014, IU’s Board of Trustees adopted President Michael A. McRobbie’s Bicentennial Strategic Plan for Indiana University, which included a third five-year investment of $5 million for the New Frontiers seed funding program, allowing for grants to continue to be offered through 2019.

Visiting NIH Program Officials Will Present Programs and Initiatives Supporting Women Researchers in the Health and Life Sciences and Beyond

When: Monday, September 21, 2015 | 1:00pm - 2:30pm
Where: University Library, 0130 Lilly Auditorium

Jennifer Plank-Bazinet, Ph.D.

Jennifer Plank-Bazinet, Ph.D.

Reiko Toyama, Ph.D.

Reiko Toyama, Ph.D.

Jennifer Plank-Bazinet, Ph.D., and Reiko Toyama, Ph.D., both from the National Institutes of Health (NIH), will be discussing NIH programs that support the hiring, advancement, and retention of women in the academic and scientific workforce. Although this presentation is targeted to “women of color” (broadly defined) at all stages of their careers, it is also open to men and/or women who do not identify as women of color but are interested in supporting women of color in scientific/research careers, including graduate students.

Dr. Plank-Bazinet will provide an overview of programs supported by the Office of Research on Women’s Health, including the Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers and the Working Group on Women in Biomedical Careers. Special attention will be given to initiatives to support women of color.

Dr. Toyama will discuss her career trajectory and training and research programs supported by the Eunice Kennedy Shriver National Institute of Child Health and Development, including the Research Supplements to Promote Diversity in Health-related Research. She will talk about the intramural research opportunities at NIH.

IUSM's Broxmeyer receives NIH grant for top-scoring hematology center

Hal E. Broxmeyer, Ph.D., and Edward Srour, Ph.D., are the principal investigators behind the recent National Institutes of Health NIDDK U54 grant that will fund a Cooperative Hematology Specialized Core Center (CHSCC). It is one of only three such funded centers by NIDDK in the United States and is the top scoring center among all competitors.

The center brings together 28 scientific and clinical researchers whose activities are focused on various aspects of nonmalignant hematology and whose work is highly dependent on one or more of the four biomedical research CHSCC cores funded, which include Experimental Mouse Resources, Optical Microscopy, Angiogenesis, and Flow Cytometry.

The central theme of the CHSCC is the regulation of human and murine hematopoiesis at the level of hematopoietic stem (HSC) and progenitor (HPC) cells.  The goal of the investigations is to leverage different components of the hematopoietic system to improve the advancement of the clinical utility and efficacy of HSC/HPC-based therapies. The center’s funding will allow the investigators to better understand basic biological processes that affect hematopoietic stem cell behavior both in vitro and in vivo in a basic science laboratory and to establish clinical trials that transform these findings into translational efforts.

CHSCC membership includes a group of well-funded investigators with diverse but complementary experience in experimental and clinical stem cell transplantation, signaling in and regulation of HSC and HPC, developmental emergence of fetal hematopoiesis, gene transfer, interactions between HSC and the hematopoietic niche, mobilization, homing and engraftment of HSC, modulation of function of freshly isolated and ex vivo manipulated HSC, and functional status of HSC after exposure to ionizing radiation.

The program includes a pilot and feasibility project that is funded in part through institutional funds to enhance the training of young investigators and to enhance their ability to successfully compete for extramural (e.g., NIH) funding. The center has a well-developed enrichment program to advance the development of both young and established CHSCC members. The CHSCC thus represents an assembly of critical cores and investigators that will advance clinical translation.

School of Medicine offers new biomarker core

Aushon Ciraplex will be a new addition to the BioPlex Biomarker core beginning this September. This multiplex platform technology is capable of simultaneous detection of multiple cytokines and offers “Ultrasensitive Cira Assays”, which can detect femtogram / mL levels of protein. Arrays are available for human, mouse, porcine, bovine, primate, and rats. 

This seminar is being sponsored by Aushon and food and drink will be served. To RSVP and/or schedule an individual meeting with Aushon personnel on September 2 or 3, please contact Jim Jean at



Best interest of the child: Improving health, well-being of low resource country orphans

Young children outside Lewa Homes

Young children outside Lewa Homes, an orphanage on the outskirts of Eldoret, Kenya.

With the support of a second grant of more than $3 million from the National Institutes of Health, researchers from the Regenstrief Institute, Indiana University, Brown University, the University of Toronto, and Moi University in Eldoret, Kenya are building upon their landmark study of Kenyan orphans which found that those living in orphanages were healthier, both physically and mentally, than those living with extended family members. The new study will investigate the causes of this disparity.

Care for orphans is a major issue throughout Africa. An estimated 153 million children and adolescents, the majority in low- and middle-income countries, have lost one or more parents. Compared to those living with parents, orphans are at a higher risk of HIV infection, malnutrition, childhood diseases, stigma and discrimination.

The new research is a five-year extension of the Orphaned and Separated Children's Assessment Related to their Health and Well-Being study, known as OSCAR. Half of the 2,859 Kenyan orphans (age less than one year to 18 years when initially enrolled in OSCAR) in the study reside in orphanages, and half live with extended family members.

From data acquired during the first 5 years of the Orphaned and Separated Children's Assessment Related to their Health and Well-Being study, now known as OSCAR 1.0, the researchers compared the physical and mental health, nutrition and education of institutionalized orphans with orphans living with family members. With the new funding, the researchers plan to determine what it is about these dissimilar environments that account for differing outcomes. They will also investigate the cost-effectiveness of the different care structures.

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NIH grant will fund IUPUI research into collagen's role in bone fracture resistance

Joseph Wallace, Ph.D.

Joseph Wallace, Ph.D.

A biomedical engineering researcher at Indiana University-Purdue University Indianapolis has received a $419,000 National Institutes of Health grant to uncover why mechanical stimulation of bones increases their resistance to fractures.

Discovery of the biological mechanisms behind that would advance research on whether collagen's physical properties in bone can be manipulated to increase fracture resistance in patients suffering from diseases related to bone fragility, said Joseph Wallace, assistant professor of biomedical engineering in the Purdue School of Engineering and Technology at IUPUI.

“We think, based on evidence in the lab, that mechanical loading is beneficial to bone function, but no one really knows how or why,” Wallace said. “The question this research is designed to answer is what is happening to drive that on a biological, molecular and cellular level?”

Most people think bones are static, he said. “Nothing could be further from the truth. Bone is one of the most metabolically active tissues in the body. It has the ability to rapidly change its size and shape according to the type of loading it encounters.”

When people walk or run, for example, they put a load, or force, on their bones. The bones sense this and respond. In the lab, mechanical loads can be controllably placed on a bone by a machine.

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New student finds home at IUPUI

ET faculty Andres Tovar and freshman Gillian Bundles

Freshman Gillian Bundles got a head start on her IUPUI career, working with Engineering and Technology faculty member Andres Tovar in this summer's Diversity Research Scholars Program.

Gillian Bundles is used to dealing with obstacles. The freshman in the School of Engineering and Technology overcame major challenges to become the 2015 valedictorian of Broad Ripple High School, an achievement that merited financial support from the School of Engineering and Technology and the IUPUI Senior Academy.

Bundles also earned a spot in this summer’s Diversity Scholars Research Program as a member of mechanical engineering faculty member Andres Tovar’s research team, exploring vehicle safety.

But her biggest accomplishment was overcoming homelessness after her mother departed, leaving Bundles with her aunt, and relying on the support of family and friends that provided places to eat, sleep and study.

“Gillian has an amazing story,” said Terri Talbert Hatch, the School of Engineering and Technology’s assistant dean of student services. “She obviously is an excellent student, but to overcome the things she has faced in her life is truly compelling. She doesn’t let it define her.”

Despite her status as a 21st Century Scholar, her college plans were up in the air throughout much of her high school career.

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IUSM Orthopaedic Surgery partners with NASA and Department of Defense

Dr. Melissa Kacena and her lab team

Dr. Melissa Kacena and her lab team performing their pilot study before they left for NASA Ames in California for their ground study on August 17.

The IU School of Medicine Department of Orthopaedic Surgery, NASA, and the U.S. Department of Defense are partnering to study bone regeneration and to make new discoveries in bone regeneration for osteoporosis, bone healing for fractures, and bone disorders.

This project is under the leadership of Melissa Kacena, Ph.D., associate professor of orthopaedic surgery, August M. Watanabe Translational Scholar and Showalter Scholar. Todd McKinley, M.D., professor of orthopaedic surgery, Tien-Min Gabriel Chu, D.D.S., Ph.D., associate professor of restorative dentistry and orthopaedic surgery and interim associate dean for research at the IU School of Dentistry, and their research teams complete the IU collaborators for the project, Bone Healing in Space.

The mission will launch on February 3 from Cape Canaveral, Fla., and travel to the International Space Station via the SpaceX Falcon spacecraft. IUSM orthopaedic researchers will manage the research project from Kennedy Space Center while working with astronauts aboard the space station to perform the laboratory work.

Long-Term Space Flight

Astronauts in spaceflight experience bone loss at an alarming rate. In fact, during a single month, an astronaut in space will lose the same amount of bone that someone on Earth with osteoporosis loses in an entire year. While experts have some understanding of how this happens, the exact causes remain unclear, and therefore this research could provide an understanding of the causes of bone loss in space and the potential medical needs of astronauts during long-term spaceflight missions.

Fracture-Healing for Military and Beyond

Extreme bone injuries, like those military personnel receive from explosives, can be so severe that amputation is the only treatment. Through this bone-healing research, a novel therapy will be examined that could potentially enhance bone regeneration and create a better alternative treatment to amputation.

Preparing for and managing a research mission in space is expensive. The total costs to the IU investigators is expected to exceed $300,000. Through grants and generous donations, a portion of the IU mission expenses is already funded, but additional support is needed. IUSM faculty and staff are invited to join the mission with a gift to the Spaceflight and Beyond Research Fund by contacting Georgia Strickland Sinclair, IUSM gift development office.

To learn more about these missions and the positive impacts they could have, visit the research website and subscribe to the blog.



Funding Opportunities for Research Commercialization and Economic Success (FORCES):
The FORCES program is designed to support IUPUI researchers in the successful transformation of their research findings into commercially viable outcomes. The key goals of FORCES are to support: 1) realization of short-term projects that will enhance commercial value of IUPUI intellectual property assets, by facilitating commercialization of inventions, technologies, or other intellectual property derived from existing research projects, and 2) development of research initiatives that show great promise for commercialization of the research outcomes. The next RTR application deadline is September 15. For grant guidelines and application forms, go to

Research Support Funds Grant (RSFG):
The Research Support Funds Grant (RSFG) program is designed to enhance the research mission of IUPUI by supporting research projects and scholarly activities that are sustainable through external funding. The next RSFG application deadline is October 15. For grant guidelines and application forms, go to

International Research Development Fund (IDF) GRANT:
The IRDF grant was developed to enhance the international research and scholarly activity focus of the IUPUI academic mission. Generally, the IRDF grant serves as venture capital to stimulate additional funding for international research and scholarly activity, which has strong potential to generate indirect cost recovery from extramural sources. The next IRDF application deadline is November 15. For grant guidelines and application forms, go to



IU New Frontiers Grant Programs

New Frontiers of Creativity and Scholarship grants of up to $50,000 to assist in the development of innovative works of scholarship or creative activity (deadline October 15, 2015)

New Frontiers Experimentation Fellowships of up to $15,000 to fund the very preliminary stages of new trajectories in research or creative activity (deadlines January 15, 2016 and June 15, 2016)

New Frontiers/New Currents grants of to $20,000 to fund workshops, symposia, or small conferences with major distinguished thinkers on timely topics of significant and broad interest (deadlines September 15, 2015 and March 1, 2016)

New Frontiers Exploratory Travel Fellowships of up to $3,000 to support national and international travel for faculty pursuing new and innovative research projects (deadlines October 15, December 15, February 15, April 15)

All Indiana University tenured and tenure-eligible faculty are eligible to apply. Those employed at IU but not on the tenure-track, whose evaluation criteria include research or creative activity, are eligible to submit proposals with an explanation of the importance of research or creative activity to their evaluation in the letter of support from their chair or dean. Visiting and adjunct faculty, part-time faculty, post-doctoral fellows, and graduate students are not eligible.


OVCR Events and Workshops

Finding Funding

Target Audience: Faculty, Staff, Graduate Students
When: Thursday, October 1, 2015 | 10:00am - 11:30am
Where: University Library, Room 0106

This session will provide an overview of the various types of external funding sources, identify tools to locate funding opportunities, explain how to design a funding search, and demonstrate a couple of knowledge management systems that contain thousands of funding opportunities available by the university subscription. This session is hands-on in a computer lab.


Developing Complex, Multi-Investigator, Multi-Institutional Proposals

Target Audience: Senior Faculty with Previous or Current External Funding; Signature Center Directors
When: Tuesday, October 13, 2015 | 4:00pm - 5:30pm
Where: University Library, Room 1126

The current funding environment favors large, complex, multi-institutional, multi-investigator projects. However, organizing a successful submission takes a great deal of planning and teamwork. This session will focus on how to prepare a successful proposal and identifying what support is available from the Proposal Development Services professional proposal writers and editors in the Office of the Vice Chancellor for Research.


IUPUI Imaging Research Symposium

Target Audience: Academic and industrial investigators interested in imaging research and its applications

When: Friday, October 16, 2015 | 1:00pm - 5:00pm
Where: University Library, Lilly Auditorium

The objective of this symposium is to bring together investigators from diverse scientific disciplines with imaging technology experts to explore potential collaborative research opportunities.

This year’s event will focus on advances in cardiovascular imaging and will include presentations by Abass Alavi, M.D. (University of Pennsylvania), Sharon Moe, M.D. (Indiana University School of Medicine), Manuel Navedo, Ph.D. (UC-Davis), Ji-Xin Cheng, Ph.D. (Purdue University) and Craig Goergen, Ph.D. (Purdue University).  In addition, a poster session will provide the opportunity for attendees to interact with several IUPUI investigators who develop or utilize cardiovascular imaging technologies in their research.  The target audience includes researchers within the IUPUI/IU/PU community as well as academic and industrial investigators within the greater Indiana research community.


Nine Golden Rules to Succeed in Research and Scholarship

Target Audience: Faculty
When: Friday, October 23, 2015 | 11:00am - 1:00pm
Where: University Library, Room 1116

This session will reveal the Nine Golden Rules on how to succeed in research and scholarship. It is focused toward new and early career investigators; however, mid-career faculty should find information of interest as well.


IUPUI Nanotechnology Research Forum and Poster Symposium

When: Friday, October 23, 2015 | 1:00pm - 5:00pm
Where: University Library, Lilly Auditorium

This symposium brings together investigators from diverse scientific disciplines with nanotechnology expertise to present and explore potential collaborative research opportunities.

More information and registration coming soon.

IUPUI Innovation Forum and Showcase - Alternatives for Funding New Ventures

Target Audience: Faculty
When: Wednesday, November 4, 2015 | 1:00pm - 4:00pm
Where: Campus Center Theater

The Office of the Vice Chancellor for Research and the Indiana University Research & Technology Corporation (IURTC) co-sponsors the IUPUI Innovation Forum and Showcase.

More information and registration coming soon.




Ask an Expert

Ask an Expert

Every Tuesday at Noon
Location: Monument Circle
Free Admission

Is it Tuesday? Is it lunchtime? Then come down to Monument Circle. Each week, you will get to meet university experts and ask them any question you want about their area of expertise. In exchange, our experts will ask you about your expertise. It's always fun, and you never know what you're going to learn.

Our upcoming Ask an Expert events are:

God and Country with Ray Haberski (8 September)

Art Therapy with Juliet King (15 September)

Christianity and Globalization with Joseph Tucker Edmonds (22 September)

Art and Anthropology with Fiona McDonald (29 September)

Women in Politics with Kristy Sheeler (6 October)

Science Fiction and Philosophy with Jason Eberl (13 October)
“Ask an Expert” was designed by the IAHI and the Kinetic Project. We are currently offering this program as a collaboration with Big Car and its SPARK: Monument Circle project.



Grants and Awards – June 2015

Bell, Richard L


Rodents with Genetic Differences in Alcohol Preference




Truitt, William A


Neural regulation of social familiarity induced anxiolysis




Hainline, Bryan E.


ISDH/NS 200-16/#613 Newborn Screening/Biochemical Services:  Statewide Program for the Identification, Prevention and Treatment of Inborn Errors of Metabolism




Burr, David B.


Comprehensive Training Program in Musculoskeletal Research




Hundley, Heather Ann


Mechanisms regulating RNA editing at specific sites in the transcriptome




Hainline, Bryan E.


Indiana University Medical Genetics Project #130




Zunich, Janice


I.U. Northwest Genetics




Prasain, Nutan


Human iPS cell-derived Mesoderm Specification to Endothelial Colony forming Cells




Miller, Kathy D.


Impact of LOFT training on muscular recovery after breast cancer treatment




Cummins, Theodore R


Sodium channel function and pharmacology in posttraumatic injury epileptogenesis




Lahiri, Debomoy K.


Neuroprotective Role of SOAP (Soluble 6myloid Precursor Protein) in Brain Injury and TBI




Wu, Xiangbing


RhoA/Rho kinase inhibition-mediated neuroprotection after spinal cord injury




Chen, Jinhui


Pharmacological manipulation of adult-born hippocampal neurons to rescue memory in a mouse model of traumatic brain injury




Rodgers, Richard B


Investigation of a Novel Hemoadsorption System in Rats with Traumatic Brain Injury




White, Fletcher A


Novel therapeutic strategies against traumatic brain injury-induced neuroinflammation and chronic pain




Griffith, Christopher Blair


Statewide Program for the Followup of  Children with Positive Newborn Screening for Cystic Fibrosis




Eugster, Erica A.


Indiana Congenital Hypothyroidism and Congenital Adrenal Hyperplasia Follow-Up Programs (ICHFP & ICAHFP)




Gunst, Susan J


Novel role of Rho kinase in smooth muscle contraction & inflammation






Funding opportunities in this section include selected current grant announcements from federal agencies for new initiatives and changes to existing programs. Announcements with limited scope are not listed here but instead are sent directly to IUPUI School Deans. For comprehensive coverage of funding opportunities, please use the links below to search online tools.


Lymphatics in Health & Disease in the Digestive System, Kidney, and Urinary Tract (R01): This opportunity is to encourage applications for research into aspects of lymphatic vessel physiology, development and pathophysiology related to health and diseases of the digestive system, kidney, and urinary tract organs. However, studies with the major focus on immune mechanisms are not encouraged. Studies to understand the factors that control local lymphatic vessel functional anatomy and physiology and development during health or disease in these organs/systems, and the mechanisms by which alterations of lymphatic vessel function affect organ function, are of interest. Deadlines: October 5, 2015; Feb. 5, 2016.

Pelvic Floor Disorders Network Data Coordinating Center (U24): This opportunity invites applications from institutions/organizations willing to participate with the NICHD as the Data Coordinating Center in an ongoing multicenter clinical program designed to study clinical and health aspects of pelvic floor disorders in women. Pelvic floor disorders for the purpose of this FOA include urinary incontinence, fecal incontinence, pelvic organ prolapse, and other sensory and emptying abnormalities of the lower urinary and gastrointestinal tracts. Particular attention will be paid to applicants that develop innovative solutions to the challenging problems in women with pelvic floor disorders and reduce the burden of this condition in women. Deadlines: Letter of Intent: October 10, 2015; Application: November 10, 2015.

Alzheimer’s Disease Translational Center for Disease Model Resources (U54): This opportunity invites U54 Cooperative Agreement applications aiming to establish an Alzheimer's Disease Translational Center for Disease Model Resources. The purpose of the Center is to: develop the next generation of rodent animal models of AD; conduct extensive characterization and clinico-pathological staging of AD animal models using translatable biomarkers; develop translatable pharmacodynamic biomarkers for well validated therapeutic targets; develop and implement guidelines for standardized best practices for the rigorous preclinical testing of AD candidates; conduct preclinical testing of candidate AD therapeutics and transparent reporting. Deadlines: Letter of Intent: December 11, 2015; Application: January 11, 2016.


Dynamics of Coupled Natural and Human Systems (CNH): The Dynamics of Coupled Natural and Human Systems (CNH) Program supports interdisciplinary research that examines human and natural system processes and the complex interactions among human and natural systems at diverse scales. Research projects to be supported by CNH must include analyses of four different components: (1) the dynamics of a natural system; (2) the dynamics of a human system; (3) the processes through which the natural system affects the human system; and (4) the processes through which the human system affects the natural system. CNH also supports research coordination networks (CNH-RCNs) designed to facilitate activities that promote future research by broad research communities that will include all four components necessary for CNH funding. Deadline: November 17, 2015.

Collaborative Research in Computational Neuroscience (CRCNS) – Innovative Approaches to Science & Engineering Research on Brain Function: Computational neuroscience provides a theoretical foundation and a rich set of technical approaches for understanding complex neurobiological systems, building on the theory, methods, and findings of computer science, neuroscience, and numerous other disciplines.

Through the CRCNS program, participating organizations of the National Science Foundation (NSF), the National Institutes of Health (NIH), and the German Federal Ministry of Education and Research (BMBF) support collaborative activities that will advance the understanding of nervous system structure and function, mechanisms underlying nervous system disorders, and computational strategies used by the nervous system. Two classes of proposals will be considered in response to this solicitation: 1) Research Proposals describing collaborative research projects, and 2) Data Sharing Proposals to enable sharing of data and other resources. Deadline: October 29, 2015.

Integrative Paleoanthropology Grants (IPG): The goal of the competition is to further innovative, integrative research to elucidate hominin biological and behavioral evolution. The particular focus is on long term processes within hominin evolution and how they relate to major questions of paleoanthropological significance. While the intellectual scope of the competition is thus constrained, the potential methodologies and disciplines are not. It is understood, for example, that fields such as cognitive science, genetics, and spatial or mathematical modeling may be directly relevant to such an endeavor.

Competition organizers recognize that much paleoanthropological research is currently interdisciplinary and integrative in nature. However, the competition is intended to stimulate research that is integrative and crosses intellectual/disciplinary boundaries in novel ways, above and beyond current practice. As general examples, an integrative and interdisciplinary project might: 1) encompass broader perspectives, not previously synthesized, on regional and large-scale comparative issues, or 2) result in the development and application of an innovative method informed by multiple disciplines. Proposals are required to address this issue directly in the project description by using up to two pages of the 15 to specifically speak to how the proposed research is both integrative and novel beyond norms currently in practice & how the proposed research could not be accomplished otherwise. Deadline: April 6, 2016.


Neurosensory & Rehabilitation Research Award: The goal of the DMRDP is to advance the state of medical science in those areas of most pressing need and relevance to today's battlefield experience. The objectives of the DMRDP are to discover and explore innovative approaches to protect, support, and advance the health and welfare of military personnel, families, communities, and the general public; to accelerate the transition of medical technologies into deployed products; and to accelerate the translation of advances in knowledge into new standards of care for injury prevention, treatment of casualties, rehabilitation, and training systems that can be applied in theater or in the clinical facilities of the Military Health System. Applications from investigators within the military services are highly encouraged, as are applications involving multidisciplinary collaborations among academia, industry, the military services, and the Department of Veterans Affairs (VA). Deadlines: Pre-Application: December 10, 2015; Application: February 11, 2016.

NOTE: All faculty, researchers, and scientists on continuing contracts at IU interested in applying for Department of Defense funding are eligible for assistance by the consulting firm--Cornerstone Government Affairs-- arranged by the Vice President for Research. Those interested in securing assistance from Cornerstone must submit a two-page summary of their research project and a CV or biosketch to the VP for Research Office at . Prior to submission, the IUPUI Office of the Vice Chancellor for Research is offering assistance with the two-page summaries. For more information, contact Ann Kratz


Scientific Discovery through Advanced Computing (SciDac)-High Energy Physics: The mission of the High Energy Physics (HEP) program is to understand how the universe works at its most fundamental level, which is done by discovering the elementary constituents of matter and energy, probing the interactions between them, and exploring the basic nature of space and time. This mission is executed through a program in particle physics that advances three frontiers (cosmic, energy, and intensity) of experimental scientific discovery and related research in theory, computing, and technology.

This opportunity invites new research proposals in Computational High Energy Physics that enable and accelerate discovery along the HEP science drivers and research priorities as identified in the P5 Report. Specific science topics may include but are not limited to exploring the dark universe, computational lattice gauge theory, and accelerator modeling and simulation that will advance the HEP mission by fully exploiting leadership class computing resources. Proposed computational research under this program should specify the new science that the research will make possible, and make the case why advanced computing and the SciDAC partnerships are needed for success. Deadlines: Letter of Intent: December 3, 2015; Application: January 7, 2016.



On-line search tools are available to IUPUI investigators who are interested in identifying funding opportunities in their areas of interest.

Community of Science (COS) Pivot: Pivot is a primary on-line search tool for identifying funding opportunities. To take advantage of this tool, register at Once you have completed the short registration process, you can personalize your search by selecting the option entitled “launch your workbench”. You can access federal, local, corporate, foundation, nonprofit and other funding opportunities using key terms and save the results of up to 20 searches and have them delivered to you weekly via email.

National Institutes of Health (NIH) “NIH Guide”: To take advantage of this search tool, register at It allows you to receive discipline specific funding opportunities that are delivered to you weekly via email.

National Science Foundation (NSF) “MyNSF”:To take advantage of this search tool, register at
. It allows you to receive discipline specific funding opportunities that are delivered to you weekly via email.

Federal Business Opportunities “FedBizOpps”: FedBizOpps is the single government point-of-entry for Federal government procurement opportunities over $25,000. To take advantage of this search tool, visit Opportunities found at this site include, but are not limited to, presolicitations and special notices for research and service contracts for specific projects and some national centers and surveys that would not be found in and may not be found in the Community of Science.

Limited Submission Funding Opportunities:

Many federal agencies and foundations offer grants, awards and fellowships that limit the number of applications that can come from one institution or require special handling. In order to comply with agency and foundation guidelines and increase the chances of Indiana University (IU) succeeding in such limited submissions and special handling opportunities, IU policies and procedures are in place and are utilized by the Office of the Vice Chancellor for Research and other IU research offices to facilitate internal coordination and competitions.

Individuals interested in responding to limited submission opportunities must inform the Office of the Vice Chancellor for Research about their intent to apply to a given limited submission opportunity, such that they can be included in the internal review and selection process. Failure to do so may disqualify individuals from consideration for submission to the funding opportunity.

Individuals interested in a limited submission opportunity or have any questions about the internal coordination process, contact Etta Ward at or 317-278-8427. For a description of upcoming limited submission funding opportunities, as well as guidelines and application forms, go to: Please note that this is not a comprehensive list, and that any external funding opportunity that imposes any type of submission limitation is subject to the IU limited submission policy and procedures.


Office of the Vice Chancellor for Research -
Indiana University Purdue University Indianapolis
755 West Michigan Street, UL1140, Indianapolis, IN 46202-2896
Phone: (317) 278-8427

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